紫花前胡

中文文本参考：《中国药典（2020年版）》
English text reference: Chinese Pharmacopoeia (2020 Edition)

概述 Overview

本品为伞形科植物紫花前胡Peucedanum decursivum （Miq.）Maxim.的干燥根。秋、冬二季地上部分枯萎时采挖，除去须根，晒干。
Peucedani Decursivi Radix is the dried root of Peucedanum decursivum (Miq.) Maxim. (Fam. Umbelliferae). The drug is collected in autumn and winter when the aerial part withers, removed from rootlets, and dried in the sun.

性状 Description

本品多呈不规则圆柱形、圆锥形或纺锤形，主根较细，有少数支根，长3～15cm，直径0.8～1.7cm。表面棕色至黑棕色，根头部偶有残留茎基和膜状叶鞘残基，有浅直细纵皱纹，可见灰白色横向皮孔样突起和点状须根痕。质硬，断面类白色，皮部较窄，散有少数黄色油点。气芳香，味微苦、辛。
Roots irregularly cylindrical, conical or fusiform, main root slender, with a few lateral roots, 3-15cm long, 0.8-1.7cm in diameter; surface brown to dark brown, with occasional remains of stem base and membranous leaf sheath, shallowly longitudinally wrinkled, with grayish-white transverse lenticels-like projections and dotted rootlet scars. Texture hard, fracture white, cortex narrow, with a few yellow oil dots. Odour, aromatic; taste, slightly bitter and pungent.

鉴别 Identification

（1）本品根横切面：木栓层为数列至10余列扁平细胞，外有落皮层。栓内层极窄，有油管散在。韧皮部宽广；油管多数，类圆形，略呈多轮环状排列，分泌细胞5～10个；韧皮射线近皮层处多弯曲且形成大小不等的裂隙。形成层环状。木质部较小，导管径向排列呈放射状；木射线较宽；木纤维少见。薄壁细胞含淀粉粒。
（1）Cross-section of the root of this product: the cork layer is several columns to more than 10 rows of flat cells, with an epicortical layer outside. The inner layer of the plug is extremely narrow, and there are tubing scattered in it. Phloem broad; Most of the tubing are round, slightly arranged in a multi-wheel ring shape, and there are 5~10 secretory cells; Phloem rays are often curved and form fissures of varying sizes near the cortex. The cambium is ring-shaped. The xylem is small, and the ducts are arranged radially in a radial pattern; Wood rays are wider; Wood fibers are rare. Parenchyma cells contain starch granules.

（2）取本品粉末0.5g，加甲醇25ml，超声处理20分钟，滤过，取滤液作为供试品溶液。另取紫花前胡苷对照品，加甲醇制成每1ml含50μg的溶液，作为对照品溶液。照薄层色谱法（通则0502）试验，吸取上述两种溶液各5μl，分别点于同一硅胶G薄层板上，以乙酸乙酯-甲醇-水（8︰1︰1）为展开剂，展开，取出，晾干，置紫外光灯（365nm）下检视。供试品色谱中，在与对照品色谱相应的位置上，显相同颜色的荧光斑点。
（2）To 0.5g of the powder add 25ml of methanol, treat with ultrasound for 20 minutes, filter, and use the filtrate as the test solution. Prepare a solution containing 50μg per ml of peucedanin CRS in methanol as the Reference solution. Carry out the method for thin layer chromatography<0502>, using silica gel G as the coating substance and a mixture of ethyl acetate-methanol-water (8:1:1) as the mobile phase. Apply separately to the plate 5μl of each of the above two solutions. After developing and removal of the plate,dry in air. Examine under ultraviolet light at 365 nm. The fluorescent spot in the chromatogram obtained with the test solution corresponds in position and colour to the spot in the chromatogram obtained with the Reference solution.

检查 Examination

水分 Water

不得过12.0%（通则0832第二法）。
Not more than 12.0 per cent <0832,method 2>.

总灰分 Total ash

不得过8.0%（通则2302）。
Not more than 8.0 per cent <2302>.

酸不溶性灰分 Acid-insoluble ash

不得过4.0%（通则2302）。
Not more than 4.0 per cent <2302>.

浸出物 Extractives

照醇溶性浸出物测定法（通则2201）项下的热浸法测定，用稀乙醇作溶剂，不得少于30.0%。
Carry out the method for determination of ethanol-soluble Extractives <2201,the hot maceration method>, using diluted ethanol as the solvent,not less than 30.0 per cent.

含量测定 Content determination

照高效液相色谱法（通则0512）测定。
Carry out the method for high performance liquid chromatography<0512>.

色谱条件与系统适用性试验 Chromatographic conditions and system suitability test

以十八烷基硅烷键合硅胶为填充剂；以甲醇-水（40︰60）为流动相；检测波长为334nm。理论板数按紫花前胡苷峰计算应不低于1500。
Use octadecylsilane bonded silica gel as the filler; use methanol-water (40:60) as the mobile phase; detect at the wavelength of 334nm. The theoretical plate number calculated from the peak of peucedanin should not be less than 1500.

对照品溶液的制备 Preparation of reference solution

取紫花前胡苷对照品适量，精密称定，加甲醇制成每1ml含50μg的溶液，即得。
Take an appropriate amount of peucedanin CRS, accurately weigh, add methanol to make a solution containing 50μg per ml, and mix well.

供试品溶液的制备 Preparation of test solution

取本品粉末（过三号筛）约0.5g，精密称定，置具塞锥形瓶中，精密加入甲醇25ml，称定重量，浸泡1小时后超声处理（功率100W，频率40kHz）20分钟，放冷，再称定重量，用甲醇补足减失的重量，摇匀，滤过，精密量取续滤液1ml，置10ml量瓶中，加甲醇至刻度，摇匀，即得。
Take about 0.5g of the powder (passed through a No. 3 sieve) of the test drug, accurately weigh, place it in a stoppered conical flask, accurately add 25ml of methanol, weigh again, soak for 1 hour, treat with ultrasound (power 100W, frequency 40kHz) for 20 minutes, cool, weigh again, make up the loss in weight with methanol, shake well, filter, accurately measure 1 ml of the filtrate, place it in a 10ml volumetric flask, add methanol to the mark, shake well, and obtain the test solution.

测定法 Determination method

分别精密吸取对照品溶液与供试品溶液各5μl，注入液相色谱仪，测定，即得。
Accurately draw 5μl of each of the reference solution and the test solution, inject into the liquid chromatograph, and determine.

本品按干燥品计算，含紫花前胡苷（C20H24O9）不得少于0.90%。
Calculated on the dried basis, the content of peucedanin (C20H24O9) should not be less than 0.90%.

饮片 Prepared slices

紫花前胡 Peucedani Decursivi Radix

炮制 Processing

除去杂质，洗净，润透，切薄片，晒干。
Eliminate Foreign matter, wash clean, soften briefly, cut into thin slices, and dry in the sun.

性 Property

微寒。
Slightly cold.

味 Flavor

苦、辛。
Bitter and pungent.

归经 Meridian tropism

归肺经。
Lung meridian.

功能 Actions

降气化痰，散风清热。
To descend qi and transform phlegm, dispel wind and clear heat.

主治 Indications

用于痰热喘满，咯痰黄稠，风热咳嗽痰多。
Used for phlegm-heat cough with fullness in the chest, thick and yellow sputum, and cough with phlegm due to wind-heat.

用量 Dosage

3～9g。
3-9g.

用法 Administration

或入丸、散。
Or made into pills or powder.

贮藏 Storage

置阴凉干燥处，防霉，防蛀。
Preserve in a cool and dry place, protect from mold and moth.

紫花前胡

文本参考：《中国药典（2015年版）》
Text reference: Chinese Pharmacopoeia (2015 Edition)

概述 Overview

本品为伞形科植物紫花前胡Peucedanum decursivum (Miq.) Maxim.的干燥根。秋、冬二季地上部分枯萎时采挖，除去须根，晒干。
Decurrent Hogfennel Root is the dried root and rhizome of Peucedanum decursivum (Miq.) Maxim. (Fam. Umbelliferae). The drug is collected in autumn to winter when the aerial part withered, removed from rootlet, and dried in the sun.

性状 Description

本品多呈不规则圆柱形、圆锥形或纺锤形，主根较细，有少数支根，长3～15cm，直径0.8～1.7cm。表面棕色至黑棕色，根头部偶有残留茎基和膜状叶鞘残基，有浅直细纵皱纹，可见灰白色横向皮孔样突起和点状须根痕。质硬，断面类白色，皮部较窄，散有少数黄色油点。气芳香，味微苦、辛。
Irregular cylindrical, conical or fusiform, taproots relatively thin, with a few of branches, 3-15 cm long, 0.8-1.7 cm in diameter. Externally brown to blackish-brown, with shallow and straight fine longitudinal wrinkles, occasionally with remains of stems and membranous leaf sheaths at the root stock, greyish-white transverse lenticel-like protrudings and dotted rootlet scars visible. Texture hard, fracture whitish, bark part relatively narrow, scattered with a few of yellow oily spots. Odour, aromatic; taste slightly bitter and pungent.

鉴别 Identification

（1）本品根横切面：木栓层为数列至10余列扁平细胞，外有落皮层。栓内层极窄，有油管散在。韧皮部宽广；油管多数，类圆形，略呈多轮环状排列，分泌细胞5～10个；韧皮射线近皮层处多弯曲且形成大小不等的裂隙。形成层环状。木质部较小，导管径向排列呈放射状；木射线较宽；木纤维少见。薄壁细胞含淀粉粒。
（2）取本品粉末0.5g，加甲醇25ml，超声处理20分钟，滤过，取滤液作为供试品溶液。另取紫花前胡苷对照品，加甲醇制成每1ml含50μg的溶液，作为对照品溶液。照薄层色谱法（通则0502）试验，吸取上述两种溶液各5μl，分别点于同一硅胶G薄层板上，以乙酸乙酯-甲醇-水（8：1：1）为展开剂，展开，取出，晾干，置紫外光灯（365nm）下检视。供试品色谱中，在与对照品色谱相应的位置上，显相同颜色的荧光斑点。

检查 Examination

水分 Water

不得过12.0%（通则0832第二法）。
Not more than 12.0 per cent <0832, method 2>.

总灰分 Total ash

不得过8.0%（通则2302）。
Not more than 8.0 per cent <2302>.

酸不溶性灰分 Acid-insoluble ash

不得过4.0%（通则2302）。
Not more than 4.0 per cent <2302>.

浸出物 Extractives

照醇溶性浸出物测定法（通则2201）项下的热浸法测定，用稀乙醇作溶剂，不得少于30.0%。
Carry out the method for determination of ethanol-soluble extractives <2201, the hot extraction method>, using dilute ethanol as the solvent, not less than 30.0 per cent.

含量测定 Assay

照高效液相色谱法（通则0512）测定。
Carry out the method for high-performance liquid chromatography <0512>.

色谱条件与系统适用性试验 Chromatographic system and system suitability

以十八烷基硅烷键合硅胶为填充剂；以甲醇-水（40：60）为流动相；检测波长为334nm。理论板数按紫花前胡苷峰计算应不低于1500。
Use octadecylsilane bonded silica gel as the stationary phase and a mixture of methanol and water (40:60) as the mobile phase. As a detector, a spectrophotometer set at 334 nm. The number of theoretical plates of the column is not less than 1500, calculated with reference to the peak of nodakenin.

对照品溶液的制备 Preparation of the reference solution

取紫花前胡苷对照品适量，精密称定，加甲醇制成每1ml含50μg的溶液，即得。
Dissolve a quantity of nodakenin CRS in methanol to produce a solution containing 50 μg per ml as the reference solution.

供试品溶液的制备 Preparation of the test solution

取本品粉末（过三号筛）约0.5g，精密称定，置具塞锥形瓶中，精密加入甲醇25ml，称定重量，浸泡1小时后超声处理（功率100W，频率40kHz）20分钟，放冷，再称定重量，用甲醇补足减失的重量，摇匀，滤过，精密量取续滤液1ml，置10ml量瓶中，加甲醇至刻度，摇匀，即得。
Weigh accurately 0.5 g of the powder (through No. 3 sieve) to a stoppered conical flask, accurately add 25 ml of methanol and weigh. Macerate for 1 hour and ultrasonicate (power 100 W, frequency 40 kHz) for 20 minutes, cool and weigh again, replenish the loss of weight with methanol, mix well, and filter. Measure accurately 1 ml of the subsequent filtrate to a 10 ml volumetric flask, dilute with methanol to volume, and mix well.

测定法 Procedure

分别精密吸取对照品溶液与供试品溶液各5μl，注入液相色谱仪，测定，即得。
Inject accurately 5 μl of each of the reference solution and the test solution, respectively, into the column, and calculate the content.

本品按干燥品计算，含紫花前胡苷（C20H24O9）不得少于0.90%。
It contains not less than 0.90 per cent of nodakenin (C20H24O9), calculated with reference to the dried drug.

饮片 Prepared slices

紫花前胡 Decurrent Hogfennel

炮制 Processing

除去杂质，洗净，润透，切薄片，晒干。
Eliminate foreign matters, wash clean, soften thoroughly, cut into thin slices, and dry in the sun.

性 Property

微寒。
Slightly cold.

味 Flavor

苦、辛。
Bitter and pungent.

归经 Meridian tropism

归肺经。
Lung meridian.

功能 Actions

降气化痰，散风清热。
To direct qi downward, resolve phlegm, disperse wind, and clear heat.

主治 Indications

用于痰热喘满，咯痰黄稠，风热咳嗽痰多。
Phlegm-heat wheezing and fullness, yellow thick phlegm, wind-heat cough, and profuse sputum.

用量 Dosage

3～9g，或入丸、散。
3-9 g, or used in pills and powder.

用法 Administration

后下。
Add when the decoction is nearly done.

贮藏 Storage

置阴凉干燥处，防霉，防蛀。
Preserve in a cool and dry place, and protect from mould and moth.