云芝

中文文本参考：《中国药典（2020年版）》
English text reference: Chinese Pharmacopoeia (2020 Edition)

概述 Overview

本品为多孔菌科真菌彩绒革盖菌Coriolus versicolor（L. ex Fr.）Quel的干燥子实体。全年均可采收，除去杂质，晒干。
Coriolus is the dried fruiting body of Coriolus versicolor (L. ex Fr.) Quel. (Fam. Polyporaceae). It is collected all year round, cleaned of impurities, and dried.

性状 Description

本品菌盖单个呈扇形、半圆形或贝壳形，常数个叠生成覆瓦状或莲座状；直径1～10cm，厚1～4mm。表面密生灰、褐、蓝、紫黑等颜色的绒毛（菌丝），构成多色的狭窄同心性环带，边缘薄；腹面灰褐色、黄棕色或淡黄色，无菌管处呈白色，菌管密集，管口近圆形至多角形，部分管口开裂成齿。革质，不易折断，断面菌肉类白色，厚约1mm；菌管单层，长0.5～2mm，多为浅棕色，管口近圆形至多角形，每1mm有3～5个。气微，味淡。
Fruiting body solitary or several fused together, fan-shaped, semicircular or shell-shaped; 1-10cm in diameter, 1-4mm thick. Surface densely covered with velvety hairs (mycelium) of various colours, such as grey, brown, blue, purple-black, etc., forming narrow concentric bands; margin thin; lower surface greyish-brown, yellowish-brown or pale yellow, white at the sterile pore region; tubes close, mouths nearly circular to polygonal, some mouths split into teeth. Texture leathery, not easily broken; context white, about 1mm thick; tubes single-layered, 0.5-2mm long, mostly light brown, mouths nearly circular to polygonal, 3-5 per mm. Odour, slight; taste, mild.

鉴别 Identification

（1）本品纵切面：皮壳外侧为绒毛层，为长短不等的菌丝，菌丝不分枝；皮壳菌丝紧密排列，菌丝胞腔内含众多的色素颗粒。菌肉层厚，无色，菌丝排列紧密。最下方为菌管层，菌管排列整齐。
（1）Longitudinal section of this product: the outer side of the skin shell is a villous layer, which is a hyphae of unequal length, and the hyphae are not branched; The mycelium of the skin shell is closely arranged, and the mycelial cavity contains numerous pigment granules. The flesh layer of the fungus is thick, colorless, and the hyphae are closely arranged. The bottom layer is the fungus tube, and the fungus tube is arranged neatly.

（2） 取本品粗粉2g，加水20ml，置水浴中加热10分钟，滤过，取滤液2ml，加碱性酒石酸铜试液4～5滴，置水浴上加热5分钟，生成红色沉淀。
（2）To 2g of the coarse powder add 20ml of water, heat under reflux for 10 minutes, filter, take 2ml of the filtrate, add 4-5 drops of alkaline cupric tartrate TS, heat on a water bath for 5 minutes, and a red precipitate is formed.

检查 Examination

水分 Water

不得过13.0%（通则0832第二法）。
Not more than 13.0 per cent <0832,method 2>.

总灰分 Total ash

不得过6.0%（通则2302）。
Not more than 6.0 per cent <2302>.

酸不溶性灰分 Acid-insoluble ash

不得过4.0%（通则2302）。
Not more than 4.0 per cent <2302>.

浸出物 Extractives

照水溶性浸出物测定法（通则2201）项下的热浸法测定，不得少于18.0%。
Carry out the method for determination of water-soluble Extractives <2201,the hot maceration method>, not less than 18.0 per cent.

含量测定 Assay

总糖 Total sugar

取本品粗粉约5g，精密称定，置锥形瓶中，精密加水120ml，称定重量，加热回流1小时，放冷，再称定重量，用水补足减失的重量，摇匀，用脱脂棉滤过，精密量取滤液40ml，加酚酞指示液1～2滴，用氢氧化钠试液调节pH值至中性，加稀硫酸25ml，加热回流4小时，放冷，用氢氧化钠试液调节pH值至中性，精密加入碘滴定液（0.1mol/L）25ml，逐滴加氢氧化钠试液4ml，边加边剧烈振摇，密塞，置暗处放置10分钟，加稀硫酸4ml，立即用硫代硫酸钠滴定液（0.1mol/L）滴定，至近终点时，加淀粉指示液2ml，继续滴定至蓝色消失，并将滴定的结果用空白试验校正，即得。每1ml碘滴定液（0.1mol/L）相当于9.008mg的无水葡萄糖（C6H12O6）。
Weigh accurately about 5g of the crude powder, place it in a conical flask, accurately add 120ml of water, weigh accurately, heat under reflux for 1 hour, cool, weigh accurately again, make up for the loss in weight with water, shake well, filter through a defatted cotton, accurately take 40ml of the filtrate, add 1-2 drops of phenolphthalein indicator, adjust the pH value to neutral with sodium hydroxide solution, add 25ml of dilute sulfuric acid, heat under reflux for 4 hours, cool, adjust the pH value to neutral with sodium hydroxide solution, accurately add 25ml of iodine titration solution (0.1mol/L), add 4ml of sodium hydroxide solution dropwise while shaking vigorously, seal tightly, place in a dark place for 10 minutes, add 4ml of dilute sulfuric acid, immediately titrate with sodium thiosulfate titration solution (0.1mol/L) until near the end point, add 2ml of starch indicator, continue titration until the blue color disappears, and correct the titration result with a blank test to obtain the result. Each 1ml of iodine titration solution (0.1mol/L) is equivalent to 9.008mg of anhydrous glucose (C6H12O6).

单糖 Monosaccharide

精密量取总糖项下的滤液40ml，加酚酞指示液1～2滴，用氢氧化钠试液调节pH值至中性，按总糖项下方法，自“精密加入碘滴定液（0.1mol/L）25ml”起，同法操作。每1ml碘滴定液（0.1mol/L）相当于9.008mg的无水葡萄糖（C6H12O6）。
Accurately take 40ml of the filtrate under the total sugar, add 1-2 drops of phenolphthalein indicator, adjust the pH value to neutral with sodium hydroxide solution, and follow the method under the total sugar. Starting from "accurately add 25ml of iodine titration solution (0.1mol/L)", perform the same operation. Each 1ml of iodine titration solution (0.1mol/L) is equivalent to 9.008mg of anhydrous glucose (C6H12O6).

总糖的含量减去单糖的含量，即为云芝多糖的含量。
The content of total sugar minus the content of monosaccharide is the content of polysaccharide of Yunzhi.

本品按干燥品计算，含云芝多糖以无水葡萄糖（C6H12O6）计，不得少于3.2%。
Calculated on the dried product, the content of polysaccharide of Yunzhi is calculated as anhydrous glucose (C6H12O6), not less than 3.2%.

饮片 Prepared slices

云芝 Coriolus

炮制 Processing

除去杂质，洗净，干燥。
Remove impurities, wash, and dry.

性 Property

平。
Neutral.

味 Flavor

甘。
Sweet.

归经 Meridian tropism

归心、脾、肝、肾经。
Heart, spleen, liver, and kidney meridians.

功能 Actions

健脾利湿，清热解毒。
Strengthen the spleen and promote diuresis, clear heat and detoxify.

主治 Indications

用于湿热黄疸，胁痛，纳差，倦怠乏力。
Used for damp-heat jaundice, hypochondriac pain, poor appetite, fatigue, and weakness.

用量 Dosage

9～27g。
9-27g.

用法 Administration

无。
None.

贮藏 Storage

置通风干燥处。
Store in a well-ventilated and dry place.

云芝

文本参考：《中国药典（2015年版）》
Text reference: Chinese Pharmacopoeia (2015 Edition)

概述 Overview

本品为多孔菌科真菌彩绒革盖菌Coriolus versicolor（L.ex Fr.）Quel的干燥子实体。全年均可采收，除去杂质，晒干。
Coriolus Versicolour Sporphore is the dried sporphore of Coriolus versicolour (L. ex Fr.) Quel. (Fam. Polyporaceae). The drug is collected all the year, removed from foreign matter, and dried in the sun.

性状 Description

本品菌盖单个呈扇形、半圆形或贝壳形，常数个叠生成覆瓦状或莲座状；直径1～10cm，厚1～4mm。表面密生灰、褐、蓝、紫黑等颜色的绒毛（菌丝），构成多色的狭窄同心性环带，边缘薄；腹面灰褐色、黄棕色或淡黄色，无菌管处呈白色，菌管密集，管口近圆形至多角形，部分管口开裂成齿。革质，不易折断，断面菌肉类白色，厚约1mm；菌管单层，长0.5～2mm，多为浅棕色，管口近圆形至多角形，每1mm有3～5个。气微，味淡。
The single pileus fan-shaped, semi-rounded or conchoidal, usually piled as imbricated or torus-shaped of lotus flower, 1-10 cm in diameter, 1-4 mm thick. Surface densely covered with gray, brown, blue, and purplish-black hairs, arranged in the concentric circles with several colors, edge thin. The ventral part greyish-brown, yellowish-brown, or pale yellow, and white at the others, fungi tubes arranging densely, the opening almost round or polygonal, some with terminal teeth. Texture leathery, uneasily broken, fracture sub-white, about 1 mm thick, fungi tubes one layer, 0.5-2 mm, mostly pale brown, the opening subrounded or polygonal, 3 to 5 cells per mm. Odour, light; taste, weak.

鉴别 Identification

（1）本品纵切面：皮壳外侧为绒毛层，为长短不等的菌丝，菌丝不分枝；皮壳菌丝紧密排列，菌丝胞腔内含众多的色素颗粒。菌肉层厚，无色，菌丝排列紧密。最下方为菌管层，菌管排列整齐。
粉末淡黄色。孢子卵圆形，长5～7μm，直径2～3μm，壁两层，外壁平滑无色，内壁浅褐色。菌丝分4种：绒毛菌丝无色，单个或数个相连，不分枝，直径3～5μm，菌丝壁有多数颗粒性物质；骨架菌丝较粗，直径5～7μm，不分枝，壁较平直，无色；生殖菌丝壁极薄，透明，直径3～4μm，不分枝，壁平直；缠绕菌丝较细，直径1.5～4μm，常弯曲。

检查 Examination

水分 Water

不得过13.0%（通则0832第二法）。
Not more than 13.0 per cent <0832, method 2>.

总灰分 Total ash

不得过6.0%（通则2302）。
Not more than 6.0 per cent <2302>.

酸不溶性灰分 Acid-insoluble ash

不得过4.0%（通则2302）。
Not more than 4.0 per cent <2302>.

浸出物 Extractives

照水溶性浸出物测定法（通则2201）项下的热浸法测定，不得少于18.0%。
Carry out the method for determination of water-soluble extractives <2201, the hot extraction method>, not less than 18.0 per cent.

含量测定 Assay

总糖取本品粗粉约5g，精密称定，置锥形瓶中，精密加水120ml，称定重量，加热回流1小时，放冷，再称定重量，用水补足减失的重量，摇匀，用脱脂棉滤过，精密量取滤液40ml，加酚酞指示液1～2滴，用氢氧化钠试液调节pH值至中性，加稀硫酸25ml，加热回流4小时，放冷，用氢氧化钠试液调节pH值至中性，精密加入碘滴定液（0～1mol/U25ml，逐滴加氢氧化钠试液4ml，边加边剧烈振摇，密塞，置暗处放置10分钟，加稀硫酸4ml，立即用硫代硫酸钠滴定液（0.1mol/L）滴定，至近终点时，加淀粉指示液2ml，继续滴定至蓝色消失，并将滴定的结果用空白试验校正，即得。每1ml碘滴定液（0.1mol/L）相当于9.008mg的无水葡萄糖（C6H12O6）。
单糖精密量取总糖项下的滤液40ml，加酚酞指示液1～2滴，用氢氧化钠试液调节pH值至中性，按总糖项下方法，自“精密加入碘滴定液（0.1mol/L）25ml”起，同法操作。每1ml碘滴定液（0.1mol/L）相当于9.008mg的无水葡萄糖（C6H12O6）。

饮片 Prepared slices

云芝 Coriolus Versicolour Sporphore

炮制 Processing

除去杂质，洗净，干燥。
Eliminate foreign matter, wash clean, and dry.

性 Property

甘，平。
Neutral; sweet.

味 Flavor

归心、脾、肝、肾经。
Heart, spleen, liver, and kidney meridians.

功能 Actions

健脾利湿，清热解毒。
To fortify the spleen, drain dampness, clear heat, and remove toxin.

主治 Indications

用于湿热黄疸，胁痛，纳差，倦怠乏力。
Dampness-heat jaundice, hypochondriac pain, torpid intake, fatigue, and lack of strength.

用量 Dosage

9～27 g。
9-27 g.

用法 Administration

后下。
Add when the decoction is nearly done.

贮藏 Storage

置通风干燥处。
Preserve in a ventilated and dry place.