山蛩虫,中药材名。本品为山蛩科动物燕山蛩Spirobolus bungii Brandt.的全体。具有破积,解毒的功效。主治癥瘕积聚、胁下痞满、无名肿毒、瘰疬、恶疮、疬风、白秃。
Shan-qiong-chong, name of Chinese Medicinal Material. This product is the whole body of the millipede Spirobolus bungii Brandt, a member of the family Spirobolidae. It has the functions of breaking stasis and detoxification. It is mainly used for the treatment of accumulations and masses in the abdomen, fullness and oppression in the hypochondrium, unidentified swelling and toxicity, scrofula, malignant sores, eczema, alopecia areata.
NMM ID | nmm-0b1c |
系统名 | Spirobolus bungii Body |
系统中文名 | 燕山蛩全体(yān shān qióng quán tǐ) |
通用名 | Shan-qiong-chong |
通用中文名 | 山蛩虫(shān qióng chóng) |
类型 | animal |
物种基源 | Spirobolus bungii | 燕山蛩 |
药用部位 | body | 全体 |
特殊描述 | |
炮制方法 | |
系统名命名解释 | 本天然药材出自“国家中医药管理局名词术语成果转化与规范推广”项目。 山蛩虫,中药材名。本品为山蛩科动物燕山蛩Spirobolus bungii Brandt.的全体。具有破积,解毒的功效。主治癥瘕积聚、胁下痞满、无名肿毒、瘰疬、恶疮、疬风、白秃。 |
通用名命名解释 | NMMGN衍生自“国家中医药管理局名词术语成果转化与规范推广”项目相关中药材中文名。 |
上级药材 | |
下级药材 | |
创建人 | |
审核专家 |
功效作用 功能
Efficacy and Functions
破积,解毒。主治
Break up accumulation, detoxify. Mainly used for治疗
癥瘕积聚、胁下痞满、无名肿毒、瘰疬、恶疮、疬风、白秃。用法用量
Symptoms of accumulation of pathogenic factors, fullness and discomfort in the hypochondrium, unidentified swelling and toxicity, scrofula, malignant ulcers, eczema, and alopecia areata. Dosage and administration.
内服:研末,0.3-1g。外用:适量,研末撒,浸酒搽,捣烂或熬膏敷贴。注意事项
Internal use: 0.3-1g of powdered medicine. External use: apply an appropriate amount of powdered medicine, soak in alcohol, apply as a paste, or make a poultice. Please pay attention to the precautions.
本品毒性大,慎服。药理作用
This product is highly toxic, use with caution. Pharmacological effects.
抗肿瘤作用:燕山蛩醚提取物0.15-0.50g/kg、醇提取物1.2-1.3g/kg、醇醚提取物0.2g/kg分别给小鼠腹腔注射12-14d,对小鼠实体型宫颈癌生长有显着抑制作用。醇醚提取物对小鼠Lewis肺癌生长也有较显着抑制作用。三种提取物还显着抑制小鼠腹水型宫颈癌、腹水型肉瘤S180、艾围腹水瘤生长。醇醚提取物的作用在0.05-0.2g/kg剂量范围内,随剂量增加而增强。0.2g/kg剂量甚至可以完全阻断腹水型宫颈癌形成,还显着延长小鼠生存时间。燕山蛩醇醚提取物0.2ml给腹水型宫颈癌小鼠腹腔注射1次,1小时内即可引起癌细胞膜改变,造成细胞核裂解和细胞崩鼠、溶解,还能显着抑制癌细胞的有丝分裂。这种作用以给药后2小为最强,持续6小时以上。毒理作用
Anti-tumor effects: Yan Shan Qiong ether extract at doses of 0.15-0.50g/kg, alcohol extract at doses of 1.2-1.3g/kg, and alcohol-ether extract at a dose of 0.2g/kg were injected into the abdominal cavities of mice for 12-14 days, showing significant inhibitory effects on the growth of solid cervical cancer in mice. The alcohol-ether extract also exhibited significant inhibitory effects on the growth of Lewis lung cancer in mice. These three extracts also significantly inhibited the growth of ascitic cervical cancer, ascitic sarcoma S180, and ascitic Ehrlich tumor in mice. The effect of the alcohol-ether extract was enhanced within the dosage range of 0.05-0.2g/kg, with increasing dosage leading to stronger effects. A dosage of 0.2g/kg could even completely block the formation of ascitic cervical cancer and significantly prolong the survival time of mice. When 0.2ml of Yan Shan Qiong alcohol-ether extract was injected into the abdominal cavities of ascitic cervical cancer mice once, it could cause changes in the cancer cell membrane within 1 hour, leading to cell nuclear lysis, cell collapse, dissolution, and significant inhibition of cancer cell mitosis. This effect was strongest 2 hours after administration and lasted for over 6 hours. Toxic effects were also observed.
毒性:燕山蛩醇醚提取物给小鼠腹腔注射的LD50为2.733+/-0.156g/kg。小鼠亚急性毒性试验中发现给药组动物肝脏枯氏细胞肿胀,肝窦扩张,肝细胞略呈萎缩状态,萎缩程度随剂量增大而稍重,其余指标、血象等均正常。犬亚急性毒性试验中心、肝、肾等脏器均未见病理改变。相关论述
Toxicity: The LD50 of the ethyl acetate extract of Yan Shan Qiong alcohol given to mice by intraperitoneal injection is 2.733+/-0.156g/kg. In the subacute toxicity test on mice, it was found that the liver Kupffer cells of the animals in the treatment group were swollen, the liver sinusoids were dilated, and the liver cells were slightly shriveled, with the degree of shrinkage increasing slightly with the dose, while other indicators and blood parameters were normal. In the subacute toxicity test on dogs, no pathological changes were observed in the heart, liver, kidneys, and other organs. Relevant discussions.
1、《本草拾遗》:治人嗜酒不已;又敷恶疮。2、《分类草药性》:治一切痒疮,敷鱼口痈毒。3、《贵州民间方药集》治麻风,无名肿毒。4、《四川中药志》1979年版:破积解毒,举陷。用于腹中癥积,息肉,恶疮,瘰疬,子宫脱垂;近用于治皮肤癌。5、《中国药用动物志》:主治扁桃体炎及一切疮毒。临床应用 相关配伍
- "Compendium of Materia Medica Addendum": Used to treat alcohol addiction and apply to malignant ulcers.2. "Classification of Medicinal Herbs": Effective for all kinds of itchy sores and can be applied to treat fish mouth abscesses.3. "Collection of Folk Remedies in Guizhou": Treats leprosy and unidentified swellings and toxins.4. "Sichuan Materia Medica": 1979 edition: Breaks up accumulations, detoxifies, and lifts sinking. Used for abdominal accumulations, polyps, malignant ulcers, scrofula, uterine prolapse; recently used to treat skin cancer.5. "Chinese Medicinal Animals": Mainly used to treat tonsillitis and all kinds of ulcers and toxins. Relevant compatibility in clinical applications.
1、治鼻息肉:百脚陆醋炙研末,棉花蘸塞鼻孔中。(《泉州本草》)2、治急性扁桃体炎:千脚虫、鲜赤葛各适量,捣绒包颈部3、治颈淋巴结结核:千脚虫1条,五倍子12g。捣烂醋调外散。(2、3方出自《万县中草药》)4、治子宫脱垂:千脚虫1条,炕干研末,分4次,姜开水送服,隔日服1次。(《万县中草药》)加工炮制 采收加工
- Treatment for nasal polyps: Grind Centipede Herb and mix with vinegar, then dip cotton and insert into the nostrils. (From "Quanzhou Materia Medica")2. Treatment for acute tonsillitis: Take appropriate amounts of Millipede and fresh red kudzu, grind into a paste and apply around the neck. 3. Treatment for cervical lymph node tuberculosis: Use one Millipede and 12g of gallnuts, grind into a paste and apply externally with vinegar. (The second and third remedies are from "Wanxian Chinese Herbal Medicine")4. Treatment for uterine prolapse: Use one Millipede, grind into a powder, divide into 4 doses, mix with ginger water and take once every other day. (From "Wanxian Chinese Herbal Medicine") Processing and preparation: Harvest and process.
夏季捕捉,鲜用或晒干。药材鉴别 药材性状
Summer harvest, use fresh or sun-dried. Identification of medicinal materials, medicinal properties.
多呈半环状,全长5-6mm,直径5-6mm。全体黑褐色,具50余个环节,每个环节具一棕色环,步肢多脱落。体轻,质脆,易断,断面中空。气微,味淡,有毒。植物学信息 植物种属
The body is semi-annular, with a total length of 5-6mm and a diameter of 5-6mm. The entire body is black-brown, with over 50 segments, each segment having a brown ring, and the walking legs often fall off. The body is light, brittle, easy to break, and the cross-section is hollow. It has a faint odor, tasteless, and is toxic. Botanical information about the plant species.
山蛩科山蛩属动物燕山蛩。形态特征
The Yanshan cricket belongs to the family Gryllidae and the genus Gryllus. It has distinctive morphological characteristics.
燕山蛩,体长圆形,长约120mm,宽约7mm,全体由多数环节组成,从颈板到肛节约有体节54个,触角1对,长约5mm,其基部两侧各有50个单眼集结排成三角状,似复眼。第1节无步肢,第2-4节各有步肢1对,自第5节起至肛节,每节有步肢2对,各步肢6节,末端具爪,生殖肢由第7节步肢变成。自第6背板各各体节的两侧有臭腺孔。分布区域
The Yanshan Qiong is a species of insect in the shape of a round body, measuring about 120mm in length and 7mm in width. Its body is composed of numerous segments, with approximately 54 body segments from the neck plate to the anal segment. It has a pair of antennae, about 5mm long, with 50 single eyes on each side of the base arranged in a triangular shape resembling compound eyes. The first segment lacks walking limbs, while segments 2-4 each have a pair of walking limbs. From the 5th segment to the anal segment, there are two pairs of walking limbs on each segment, with 6 segments in each pair, ending in claws. The reproductive limbs develop from the walking limbs of the 7th segment. There are scent gland pores on both sides of each body segment starting from the 6th dorsal plate. Distribution area.
全国大部分地区均有分布。生长环境
Distributed in most parts of the country. Growing environment.
多栖息于阴湿地区。
They inhabit in damp and shady areas.