篦子三尖杉,中药名。为三尖杉科三尖杉属植物篦子三尖杉Cephalotaxus oliveri Mast.的种子和枝叶。具有抗癌的功效。主治血液系统肿瘤及其他一些恶性实体瘤。
Bi-zi-san-jian-shan, name of Chinese Medicinal Material. Cephalotaxus oliveri Mast.) refers to the seeds and branches of the plant Cephalotaxus oliveri Mast., which belongs to the Cephalotaxaceae family. It has the efficacy of anti-cancer and is mainly used to treat tumors of the blood system and other malignant solid tumors.
NMM ID | nmm-09nt |
系统名 | Cephalotaxus oliveri Branch and Leaf or Seed |
系统中文名 | 篦子三尖杉枝与叶或种子(bì zi sān jiān shān zhī yǔ yè huò zhǒng zi) |
通用名 | Bi-zi-san-jian-shan |
通用中文名 | 篦子三尖杉(bì zi sān jiān shān) |
类型 | plant |
物种基源 | Cephalotaxus oliveri | 篦子三尖杉 |
药用部位 | branch | 枝andleaf | 叶orseed | 种子 |
特殊描述 | |
炮制方法 | |
系统名命名解释 | 本天然药材出自“国家中医药管理局名词术语成果转化与规范推广”项目。 篦子三尖杉,中药名。为三尖杉科三尖杉属植物篦子三尖杉Cephalotaxus oliveri Mast.的种子和枝叶。具有抗癌的功效。主治血液系统肿瘤及其他一些恶性实体瘤。 |
通用名命名解释 | NMMGN衍生自“国家中医药管理局名词术语成果转化与规范推广”项目相关中药材中文名。 |
上级药材 | |
下级药材 | |
创建人 | |
审核专家 |
功效作用 功能
The efficacy and functions.
抗癌。主治
Anti-cancer. Main treatment.
血液系统肿瘤及其他一些恶性实体瘤。用法用量
Tumors of the hematopoietic system and other malignant solid tumors. Dosage and administration.
提取其中三尖杉酯碱使用,具体参见“现代临床研究”项。注意事项
Extract of Tripterygium wilfordii Hook F. is used, please refer to the "Modern Clinical Research" section for details. Precautions should be taken.
主要副作用为骨髓抑制和消化道反应。化学成分
The main side effects are bone marrow suppression and gastrointestinal reactions. Chemical composition.
含粗榧碱,三尖杉碱,谢汉墨属碱B。叶含4',4,7,7"-四甲氧基穗花杉双黄酮,金松双黄酮,篦子三尖杉双黄酮。药理作用
It contains paclitaxel, taxane, and harringtonine B. The leaves contain 4', 4, 7, 7"-tetramethoxytaxifolin, amentoflavone, and podophyllotoxin. Pharmacological effects.
抗癌作用:从篦子三尖杉中分离的三尖杉酯碱(即粗榧碱)制备的注射液每日1mg/kg腹腔注射,共8次,对小鼠肉瘤S180的抑制率为42.3%。毒理作用
Anti-cancer effect: The injection prepared from the triptolide alkaloid (also known as triptolide) isolated from Tripterygium wilfordii Hook.f. at a dose of 1mg/kg per day via intraperitoneal injection for a total of 8 times, resulted in a 42.3% inhibition rate on S180 sarcoma in mice. Toxic effects were also observed.
三尖杉酯碱注射液给小鼠腹腔注射的LD50为4.12mg/kg。加工炮制 采收加工
The LD50 of Tripterygium wilfordii alkaloid injection for intraperitoneal injection in mice is 4.12mg/kg. Processing and preparation involve harvesting and processing.
枝叶全年均可采;种子在秋季成熟时采收,晒干。植物学信息 植物种属
Branches and leaves can be harvested all year round; seeds are harvested and dried in autumn when they mature. Botanical information about the plant species.
三尖杉科三尖杉属植物篦子三尖杉。形态特征
The Taxaceae family includes the genus Taxus, and the plant you are referring to is the Taxus cuspidata. Here are its morphological characteristics.
灌木,高达4m。树皮灰褐色。叶条形,质硬,排成紧密的2列,长1.5-3.2cm,宽3-4.5mm,中部以上向上弯曲,先端凸尖,基部截形或近心形截形,近无柄,上面深绿色,微拱圆,中脉稍明显或仅中下部明显,下面气孔带白色,较绿色边缘带宽1-2倍。雄球花6-7,聚生成头状花序,径约9mm,有雄蕊6-10;雌球花的胚珠通常1-2枚,发育成种子。种子倒卵圆形、卵圆形或近球形,长2.7cm,径1.8cm,先端有小尖头,有长梗。花期3-4月,种子成熟期9-10月。分布区域
Shrub, up to 4m tall. The bark is gray-brown. The leaves are linear, hard in texture, arranged in two tight rows, 1.5-3.2cm long, 3-4.5mm wide, with the upper part curving upwards, the apex convex and pointed, the base truncate or nearly cordate, nearly sessile, dark green on the upper surface, slightly arched, with the midrib slightly prominent or only prominent in the middle and lower part, and with white stomatal bands on the lower surface, about 1-2 times wider than the green edge. The male flowers are 6-7, clustered into head-like inflorescences, about 9mm in diameter, with 6-10 stamens; the ovules of the female flowers usually develop into 1-2 seeds. The seeds are inverted ovate, ovate, or nearly spherical, 2.7cm long, 1.8cm in diameter, with a small pointed tip at the apex and a long stalk. The flowering period is from March to April, and the seed maturity period is from September to October. Distribution area.
分布于西南及江西、湖北、湖南、广东等地。生长环境
Distributed in the southwest, as well as Jiangxi, Hubei, Hunan, Guangdong, and other regions. Growing environment.
生于海拔300-1800m的针叶树、阔叶树林中,喜温暖湿润气候及酸性山地黄壤。
It grows in coniferous and broad-leaved forests at an altitude of 300-1800 meters, and prefers a warm, humid climate and acidic mountain yellow soil.