净草问荆:净制草问荆
Jing-cao-wen-jing: Cao-wen-jing processed by cleaning.

功效作用 功能
Efficacy and Functions

活血，利尿，驱虫。主治
Promoting blood circulation, diuresis, and expelling parasites. Mainly used for治疗.

动脉粥样硬化，小便涩痛不利，肠道寄生虫病。用法用量
Atherosclerosis, dysuria with painful urination, and intestinal parasitic infections. Dosage and administration.

内服：煎汤，5-10g，鲜品30-60g。化学成分
Internal administration: Decoction, 5-10g, fresh product 30-60g. Chemical composition.

含山柰酚-3-双葡萄糖甙，山柰酚-3-芸香糖甙，山柰酚-3，7-双葡萄糖甙，槲皮素-3-芸香糖-7-葡萄糖甙，槲皮素，山柰酚。药理作用
The pharmacological effects of phloridzin-3-O-glucoside, phloretin-3'-O-rhamnoside, phloridzin-3,7-O-diglucoside, quercetin-3-O-rhamnosyl-glucoside, quercetin, and phloretin include...

1、降压作用：草问荆水提取液（1：1）对家兔不同途径给药（灌服、腹胺注射、静脉注射）都有非常显着的降压作用，口服降压维持3-6h，较政党血压下降31.2%（平均值），反复应用无快速耐受性。草问荆水提取液使乙酰胆碱的降压作用增敏，M-胆碱能受体阴滞药阿插品给与后，其降压作用减弱或消失。草问荆有抑制肾上腺素的升压作用；对阻断颈总动脉血流所致加压反应有抑制作用；切断迷走神神经后降压作用显着减弱，故认为草问荆有中枢抑制作用。2、抗心肌缺血作用：草问荆提取取物（1g生药/ml）静脉注射1.5-3.0g/kg对豚鼠由繁荣昌盛体后叶素所致的标准II导程心电图S-T段和T波增高、心率减慢，都有显着的对抗作用。可使心电图RR、PQ、OT和ORS间期较给药前显着延长。草问荆提取物10-15g/kg给小鼠腹腔注射，能提高在低压和常压条件下耐缺氧能力，增强预先给与异丙肾上腺素所致的耐缺氧能力，使小鼠耗氧率较对照组降低32.8%。心肌86Rb摄取率在低剂量组（10g/kg）和高剂量组（15g/kg）较对照组分别降低8.2%、26.4%；并能对抗异丙肾上腺素所致心肌与血浆Camkp含量增高。3、中枢神经抑制作用：用草问荆提取液0.2g/10g或0.4g/10g给小鼠灌胃能加强戊巴比妥钠的催眠作用，使入昨所需时间缩租及昨眠时间延长。草问荆在0.2g/140g腹腔注射给药时，对小鼠有微弱的对抗士的宁惊劂作用，能延长惊劂潜伏期；同样剂量亦能明显延长小鼠对尼可刹米惊厥的潜伏期。在热板法证明草问荆提取液0.2g/10g腹腔注射有明显镇痛作用。毒理作用

1. Hypotensive effect: The extract of Cao Wen Jing Shui (1:1) has a very significant hypotensive effect on rabbits through different routes of administration (oral, intraperitoneal injection, intravenous injection). The oral hypotensive effect can last for 3-6 hours, with an average blood pressure decrease of 31.2%. There is no rapid tolerance observed with repeated use. The extract sensitizes the hypotensive effect of acetylcholine, and the hypotensive effect is weakened or disappears when given with the M-cholinergic receptor antagonist atropine. Cao Wen Jing Shui has an inhibitory effect on the pressor action of adrenaline, inhibits the pressor response caused by blocking blood flow in the carotid artery, and significantly weakens the hypotensive effect after cutting the vagus nerve, indicating a central inhibitory effect.2. Anti-myocardial ischemia effect: Intravenous injection of Cao Wen Jing extract (1g crude drug/ml) at a dose of 1.5-3.0g/kg in guinea pigs has a significant antagonistic effect on the ST segment and T wave elevation and bradycardia induced by posterior pituitrin in standard II lead electrocardiogram. It can significantly prolong the RR, PQ, QT, and QRS intervals compared to before administration. Intraperitoneal injection of 10-15g/kg of Cao Wen Jing extract in mice can improve the tolerance to hypoxia under low and normal pressure conditions, enhance the tolerance to hypoxia induced by isoproterenol pre-administration, and reduce the oxygen consumption rate by 32.8% compared to the control group. The myocardial 86Rb uptake rate in the low-dose group (10g/kg) and high-dose group (15g/kg) decreased by 8.2% and 26.4% respectively compared to the control group, and it can counteract the increase in myocardial and plasma Camkp levels induced by isoproterenol.3. Central nervous system inhibitory effect: Intragastric administration of Cao Wen Jing extract at doses of 0.2g/10g or 0.4g/10g in mice can enhance the hypnotic effect of pentobarbital, shorten the onset time of sleep, and prolong the sleep time. When administered intraperitoneally at a dose of 0.2g/140g, Cao Wen Jing has a weak antagonistic effect on strychnine-induced convulsions in mice, prolonging the convulsion latency. The same dose can also significantly prolong the latency of nicotinic convulsions in mice. The intraperitoneal injection of Cao Wen Jing extract at a dose of 0.2g/10g has a significant analgesic effect in the hot plate test. Toxicological effects.

草问荆提取液给小鼠腹腔注射LD50为38.9+/-2.66g/kg，在给药后20min时，小鼠活动减弱，眼睑下垂，反射迟钝，中毒时翻正反射消失等。草问荆提取液1mg/ml按0.3ml/min恒速静脉注射，给药后平均40.4+/-3.6nub，出现ST段、T波明显上升或倒置，QRS间期延长或心律不齐。最小中毒量为26.4+/-1.95g/kg；最小致死量为31.3+/-1.7g/kg。加工炮制 采收加工
The LD50 of the extract of Herba Sagittariae given by intraperitoneal injection to mice is 38.9+/-2.66g/kg. After administration, the mice showed reduced activity, drooping eyelids, delayed reflexes, and disappearance of righting reflex when intoxicated. When the extract of Herba Sagittariae at a concentration of 1mg/ml was intravenously injected at a constant rate of 0.3ml/min, the average number of beats per minute was 40.4+/-3.6, and there were significant ST segment and T wave elevation or inversion, prolonged QRS interval, or arrhythmia. The minimum toxic dose is 26.4+/-1.95g/kg; the minimum lethal dose is 31.3+/-1.7g/kg. Processing and preparation methods are involved in the collection and processing of Herba Sagittariae.

夏季采挖，洗净，晒干或鲜用。药材鉴别 药材性状
Summer is the season for harvesting, cleaning, drying, or using fresh herbs. Herb identification and characteristics.

全草干缩，枝常脱落。茎有多数轮生的细长分枝。叶鞘齿分离，长三角形，长约1.5cm，先端尖，中部棕褐色，边缘白色膜质。气微，味淡。植物学信息 植物种属
The whole plant is dried and shriveled, with branches often falling off. The stem has numerous whorled slender branches. The leaf sheaths are toothed and separated, long and triangular, about 1.5cm long, with a pointed tip, brown in the middle, and white membranous edges. It has a slight odor and a mild taste. Botanical information about the plant species.

木贼科植物草问荆。形态特征
The plant belongs to the Huperziaceae family and is called Huperzia serrata. Here are its morphological characteristics.

多年生草本，高15-50cm。根茎横走，黑褐色。春季孢子囊茎稍呈肉质，淡褐色，有密生的绿色轮状分枝。叶鞘长约1.5cm，叶鞘齿分离，长三角形，长尖，中部棕褐色，边缘白色，膜质。营养茎单一，有锐飘然脊及刺状突起，分枝细长，常水平或成直角展开。。孢子囊穗钝头；孢子成熟时茎先端枯萎，产生分枝，渐变绿色，和营养茎同出。分布区域
Perennial herb, 15-50cm tall. Rhizomes are horizontal and dark brown. In spring, the sporangial stalks are somewhat fleshy, light brown, with densely green circular branches. Leaf sheaths are about 1.5cm long, with separated teeth, long triangular, long-pointed, brown in the middle, white at the edges, and membranous. The trophophore is single, with sharp ridges and prickly protrusions, slender branches, often spreading horizontally or at right angles. The sporangial spikes are blunt; when the spores mature, the tip of the stem withers, producing branches that gradually turn green, emerging alongside the trophophore. Distribution area.

分布于东北、华北、西北及湖北等地。生长环境
Distributed in Northeast China, North China, Northwest China, and Hubei Province, among other regions. Growing environment.

生于林内、山沟林缘、灌丛杂草等处。
Born in forests, mountain valleys, forest edges, thickets, and grasslands.