水团花，中药名。为茜草科植物水团花Adinapilulifera（Lam.）Franch.exDrake的枝叶或花、果。具有清热祛湿，散瘀止痛，止血敛疮的功效。主治痢疾，肠炎，浮肿，痈肿疮毒，湿疹，溃疡不敛，创伤出血。
Shui-tuan-hua, name of Chinese Medicinal Material. It refers to the branches, leaves, flowers, and fruits of Adinapilulifera (Lam.) Franch.exDrake, a plant of the Rubiaceae family. It has the effects of clearing heat and dampness, dispelling stasis and relieving pain, stopping bleeding and promoting healing of sores. It is mainly used for treating dysentery, enteritis, edema, carbuncles, sores, eczema, non-healing ulcers, and traumatic bleeding.

功效作用 功能
Efficacy and Functions

清热祛湿，散瘀止痛，止血敛疮。主治
Clearing heat and dampness, promoting blood circulation to remove blood stasis, stopping bleeding and promoting wound healing. Mainly used for治疗。

痢疾，肠炎，浮肿，痈肿疮毒，湿疹，溃疡不敛，创伤出血。用法用量
Dysentery, enteritis, edema, carbuncle, abscess, eczema, unhealed ulcers, and bleeding wounds. Dosage and administration.

内服：煎汤，花、果10-15g，枝叶15-30g。外用：适量，枝、叶煎水洗；或捣敷。化学成分
Internal use: Decoction, 10-15g of flowers or fruits, 15-30g of branches or leaves. External use: Appropriate amount, boil branches or leaves in water for washing; or pound for applying. Chemical components.

茎、叶含β-谷甾醇，豆甾醇及以奎诺酸，模绕醇酸，金鸡纳酸，白桦脂酸等三萜类为甙元的皂甙。药理作用
Stems and leaves contain β-sitosterol, stigmasterol, as well as saponins with triterpenoids such as oleanolic acid, maslinic acid, gymnemic acid, and betulinic acid as the aglycone. Pharmacological effects.

1、对心血管系统的作用：家兔静脉注射水团花乙酸乙酯提取物10g（生药）/kg，20g（生药）/kg，能抑制脑垂体后叶素引起的T波升高和S-T段上移，对急性心肌缺血有一定的保护作用。乙酸乙酯提取物静脉注射5g/kg，使麻醉犬平均降低血压31.1%，维持约30min，但对心率和心肌收缩力无明显影响。麻醉开胸犬静脉注射2.5g/kg，显著增加左旋支冠脉血流量60%以上，14min后恢复正常水平；对离体兔、豚鼠心脏也有扩张冠脉、增加冠脉流量作用。乙酸乙酯提取物和醇提取物还能显著延长小鼠常压耐缺氧的存活时间，提高缺氧的耐受能力。2、平喘、止咳、祛痰作用：水团花醇提取物对乙酰胆碱所致离体豚鼠气管收缩有明显的松弛作用。醇提取物按23g/kg给豚鼠腹腔注射，其平喘率为40%。醇提取物50g/kg、30g/kg分别给小鼠腹腔注射，或100g/kg灌胃，均有镇咳作用（氨水引咳法）。醇提取物80g/kg小鼠灌胃，有明显祛痰作用（酚红法）。3、抗菌作用：采用试管倍稀法，水团花醇提取物对大肠、绿脓、福氏、伤寒、枯草、蜡样杆菌及八叠、金黄色葡萄球菌均有抑制作用。毒理作用

1. Effects on the cardiovascular system: Intravenous injection of 10g (crude drug)/kg and 20g (crude drug)/kg of water caltrop ethyl acetate extract in rabbits can inhibit the elevation of T wave and upward shift of S-T segment induced by posterior pituitary lobe extract, and has a certain protective effect on acute myocardial ischemia. Intravenous injection of ethyl acetate extract at 5g/kg in anesthetized dogs resulted in an average blood pressure reduction of 31.1% maintained for about 30 minutes, with no significant effects on heart rate and myocardial contractility. Intravenous injection of 2.5g/kg in anesthetized dogs undergoing thoracotomy significantly increased the blood flow in the left circumflex coronary artery by more than 60%, returning to normal levels after 14 minutes; it also dilated coronary arteries and increased coronary blood flow in isolated rabbit and guinea pig hearts. Ethyl acetate and alcohol extracts can significantly prolong the survival time of mice under normobaric hypoxia and improve their tolerance to hypoxia.2. Anti-asthmatic, antitussive, and expectorant effects: Alcohol extract of water caltrop has a significant relaxing effect on acetylcholine-induced contraction of isolated guinea pig trachea. Intraperitoneal injection of alcohol extract at 23g/kg in guinea pigs resulted in a 40% anti-asthmatic rate. Intraperitoneal injection of alcohol extract at 50g/kg and 30g/kg in mice, or gastric gavage at 100g/kg, all have antitussive effects (ammonia-induced cough method). Gastric gavage of alcohol extract at 80g/kg in mice has a significant expectorant effect (phenol red method).3. Antibacterial effects: Using the tube dilution method, alcohol extract of water caltrop has inhibitory effects on Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Shigella dysenteriae, Bacillus subtilis, Corynebacterium diphtheriae, and Staphylococcus aureus. Toxic effects.

水团花醇提取物小鼠灌胃的LD50为332.8±12.1g（生药）/kg。水团花乙酸乙酯提取物小鼠最大耐受量为400g/kg，观察72h未见明显的毒性反应。水团花乙酸乙酯提取物20g/kg灌胃，连续3d，也未发现任何毒性反应。相关论述
The LD50 of the aqueous extract of Houttuynia cordata in mice by gavage is 332.8±12.1g (crude drug) per kg. The maximum tolerated dose of the ethyl acetate extract of Houttuynia cordata in mice is 400g/kg, with no significant toxic reactions observed after 72 hours. When administered by gavage at a dose of 20g/kg for 3 consecutive days, no toxic reactions were observed.

1、《李氏草秘》：“治金刃伤，年久烂脚疮，捣皮、叶，罨上一宿即痂。”（引自《纲目拾遗》）2、广州部队《常用中草药手册》：“清热解毒，散瘀止痛。主治痢疾，急性胃肠炎（用花果）；跌打损伤，骨折（用叶）。”3、《湖南药物志》：“清热祛湿，散瘀止痛。”临床应用 相关配伍

1. "Li's Secret Herbal Manual": "For treating wounds caused by metal objects, and chronic ulcerative foot sores, grind the skin and leaves, apply them to the affected area overnight, and scabs will form." (quoted from "Collection of Additional Notes on the Outline of Materia Medica") 2. "Guangzhou Military's Handbook of Common Chinese Medicinal Herbs": "Clears heat, detoxifies, dispels stasis, and relieves pain. Used for treating dysentery, acute gastroenteritis (using flowers and fruits); injuries from falls, fractures (using leaves)." 3. "Hunan Pharmacopoeia": "Clears heat, eliminates dampness, dispels stasis, and relieves pain." Clinical applications and relevant herbal combinations.

1、治菌痢：水团花花球10g。水煎服（沸后10min即可），每日3次。（江西《草药手册》）2、治湿热浮肿：水团花鲜茎或叶、茵陈各30g。水煎调糖服。（《福建中草药》）3、治风火牙痛：水团花鲜花球60g。水煎每日含漱数次。（江西《草药手册》）4、治痈、无名肿毒：水团花鲜叶加食盐、饭粒捣烂外敷。（《福建中草药》）5、治湿疹：（水团花）叶配杠板归，煎水洗。（《湖南药物志》）6、治创伤出血：取适量的（水团花）叶或花，以冷开水洗净，捣烂包敷于创口。（《福建民间草药》）7、治跌打扭伤：（水团花）鲜叶（量不拘），捣敷患处。（广州部队《常用中草药手册》）加工炮制 采收加工

1. Treating dysentery caused by bacteria: 10g of fresh water plantain flower heads. Decoct in water (boil for 10 minutes), take three times a day. (Jiangxi "Herbal Manual")2. Treating damp-heat swelling: 30g each of fresh stems or leaves of water plantain and Inula cappa. Decoct in water, add sugar to taste. (Fujian "Chinese Herbal Medicine")3. Treating toothache due to wind-heat: 60g of fresh water plantain flower heads. Decoct in water and use for rinsing several times a day. (Jiangxi "Herbal Manual")4. Treating carbuncles and unidentified swelling and toxicity: Fresh water plantain leaves with added salt and rice grains, mashed and applied externally. (Fujian "Chinese Herbal Medicine")5. Treating eczema: (Water plantain) leaves with Ardisia crenata, decocted for washing. (Hunan "Pharmacopoeia")6. Treating bleeding wounds: Take an appropriate amount of (water plantain) leaves or flowers, wash with cold boiled water, mash, and apply as a poultice to the wound. (Fujian "Folk Herbal Medicine")7. Treating bruises and sprains: Fresh water plantain leaves (as needed), mashed and applied to the affected area. (Guangzhou Military "Common Chinese Herbal Medicine Manual") Processing and preparation: Harvesting and processing.

枝、叶，全年均可釆，切碎，花、果，夏季采摘，洗净，鲜用或晒干。植物学信息 植物种属
Branches and leaves can be harvested all year round, chopped, and flowers and fruits can be picked in summer, washed clean, and used fresh or dried. Botanical information about the plant species.

茜草科水团花属水团花。形态特征
The water primrose belongs to the family Lythraceae and the genus Ludwigia. It has distinctive morphological characteristics.

常绿灌木或小乔木，高2m左右，可达5m。树皮灰黄白色；枝柔弱，有不整齐的近椭圆形皮孔，红棕色。叶对生；叶柄长3-10mm；托叶2裂，长5-7mm，早落；叶纸质，叶片长椭圆形至长圆状披针形或倒披针形，长3-12cm，宽1-3cm，先端长尖而钝，基部楔形，全缘，上面深绿色，两面中脉均突起，侧脉8-10对。头状花序球形，盛开时直径约1.5-2cm，单生于叶腋；总花梗长2.5-4.5cm，中下部着生轮生的5枚苞片；花萼5裂，裂片线状长圆形；花冠白色，长漏斗状，5裂，裂片卵状长圆形，长约1mm，被柔毛；雄蕊5；花盘杯状；子房下位，花柱丝状，伸出花冠管外。蒴果楔形，长约3mm。种子多数，长圆形，两端有狭翅。花期7-8月，果期8-9月。分布区域
Evergreen shrub or small tree, about 2m tall, reaching up to 5m. The bark is grayish-yellow-white; the branches are soft and weak, with irregular elliptical lenticels, reddish-brown. Leaves are opposite; petioles are 3-10mm long; stipules are 2-lobed, 5-7mm long, early falling off; leaves are papery, leaf blades are oblong to lanceolate or oblanceolate, 3-12cm long, 1-3cm wide, with a long pointed and blunt apex, cuneate base, entire margin, dark green upper surface, both midrib and 8-10 pairs of lateral veins raised on both sides. Capitulum inflorescence is spherical, about 1.5-2cm in diameter when fully open, solitary in leaf axils; peduncles are 2.5-4.5cm long, with 5 bracts arranged in a whorl in the middle-lower part; calyx is 5-lobed, lobes are linear-oblong; corolla is white, funnel-shaped, 5-lobed, lobes are ovate-oblong, about 1mm long, covered with soft hairs; stamens are 5; floral disc is cup-shaped; ovary is inferior, style is filiform, extending outside the corolla tube. Capsule is wedge-shaped, about 3mm long. Numerous seeds are oblong, with narrow wings at both ends. Flowering period is July-August, fruiting period is August-September. Distribution area.

分布于长江以南各地。生长环境
Distributed in various regions south of the Yangtze River. Growing environment.

生于海拔200-350m的山谷疏林下或旷野路旁、溪涧水畔。
Born in the valley sparse forests or open fields by the roadside, streamsides at an altitude of 200-350 meters.