硫黄

English text reference: Chinese Pharmacopoeia (2020 Edition)
中文文本参考：《中国药典（2020年版）》

Overview 概述

Sulfur is the natural element mineral sulfur of the sulfur family. It is obtained by mining, heating and melting, and removing impurities; or it is processed from sulfur-containing minerals.
本品为自然元素类矿物硫族自然硫，采挖后，加热熔化，除去杂质；或用含硫矿物经加工制得。

Description 性状

Sulfur is irregular in shape and is yellow or slightly greenish-yellow. The surface is uneven and has a greasy luster, often with many small holes. When held tightly in the hand and placed next to the ear, a slight cracking sound can be heard. It is light in weight, loose in texture, and fragile, and the fracture surface is often needle-shaped crystals. It has a distinctive odor and a mild taste.
本品呈不规则块状。黄色或略呈绿黄色。表面不平坦，呈脂肪光泽，常有多数小孔。用手握紧置于耳旁，可闻轻微的爆裂声。体轻，质松，易碎，断面常呈针状结晶形。有特异的臭气，味淡。

Identification 鉴别

When sulfur burns, it melts easily, the flame is blue, and there is a pungent odor of sulfur dioxide.
本品燃烧时易熔融，火焰为蓝色，并有二氧化硫的刺激性臭气。

Assay 含量测定

Weigh accurately about 0.2 g of the powder, place it in a conical flask, accurately add 50 ml of 0.5 mol/L ethanol potassium hydroxide titration solution, add 10 ml of water, heat in a water bath to dissolve, and evaporate the ethanol (until there are no bubbles and no alcoholic odor). Add 40 ml of water, insert a small funnel into the neck of the bottle, boil gently for 10 minutes, cool, carefully add 5 ml of hydrogen peroxide test solution , shake well, heat in a boiling water bath for 10 minutes, cool to room temperature, rinse the funnel and the inner wall of the bottle with water, add 2 drops of methyl orange indicator solution, titrate with hydrochloric acid titration solution (0.5 mol/L), and correct the titration result with a blank test. Each 1 ml of ethanol potassium hydroxide titration solution (0.5 mol/L) is equivalent to 8.015 mg of sulfur (S).
取本品细粉约0.2g，精密称定，置锥形瓶中，精密加入乙醇制氢氧化钾滴定液（0.5mol/L）50ml，加水10ml，置水浴中加热使溶解，并挥去乙醇（直至无气泡、无醇臭）。加水40ml，于瓶颈插入一小漏斗，微沸10分钟，冷却，小心滴加过氧化氢试液5ml，摇匀，置沸水浴中加热10分钟，冷却至室温，用水冲洗漏斗及瓶内壁，加入甲基橙指示液2滴，用盐酸滴定液（0.5mol/L）滴定，并将滴定结果用空白试验校正。每1ml乙醇制氢氧化钾滴定液（0.5mol/L）相当于8.015mg的硫（S）。

The content of sulfur (S) in this product shall not be less than 98.5%.
本品含硫（S）不得少于98.5%。

Prepared slices 饮片

Sulfur 硫黄

Processing 炮制

Eliminate foreign matter, break into small pieces.
除去杂质，敲成碎块。

Identification 鉴别

Same as the crude drug.
同药材。

Assay 含量测定

Same as the crude drug.
同药材。

Processed Sulfur 制硫黄

Processing 炮制

Take clean sulfur blocks, cook them with tofu, remove them when the tofu turns blackish-green, rinse them, and dry them in the shade.
取净硫黄块，与豆腐同煮，至豆腐显黑绿色时，取出，漂净，阴干。

For every 100 kg of sulfur, use 200 kg of tofu.
每100kg硫黄，用豆腐200kg。

Property 性

Warm.
温。

Toxicity 毒性

Toxic.
有毒。

Flavor 味

Sour.
酸。

Meridian tropism 归经

Kidney and large intestine meridians.
归肾、大肠经。

Actions 功能

Used externally to detoxify, kill insects, and treat sores; taken internally to tonify fire, assist yang, and promote bowel movements.
外用解毒杀虫疗疮；内服补火助阳通便。

Indications 主治

Used externally for scabies, tinea capitis, malignant ulcers, and gangrenous ulcers; taken internally for impotence and coldness in the feet, deficiency cough and cold asthma, and deficiency-cold constipation.
外治用于疥癣，秃疮，阴疽恶疮；内服用于阳痿足冷，虚喘冷哮，虚寒便秘。

Dosage 用量

Appropriate amount for external use. Internal 1.5-3g.
外用适量。内服1.5～3g。

Administration 用法

Ground into a powder and applied to the affected area with oil. After concocting, it can be taken in pills and powder.
研末油调涂敷患处。炮制后入丸散服。

Precautions 注意

Caution should be exercised in pregnant women. It should not be used with saltpeter and realgar.
孕妇慎用。不宜与芒硝、玄明粉同用。

Storage 贮藏

Store in a dry place and keep away from fire.
置干燥处，防火。

硫黄

Text reference: Chinese Pharmacopoeia (2015 Edition)
文本参考：《中国药典（2015年版）》

Overview 概述

Sulfur is the natural sulfur of natural elemental mineral group. The drug is collected and melted to remove foreign matter； or obtained by processing the minerals containing sulfur.
本品为自然元素类矿物硫族自然硫，采挖后，加热熔化，除去杂质；或用含硫矿物经加工制得。

Description 性状

In irregular masses, yellow or somewhat greenish yellow. Surface uneven, showing fatty lustre, often with numerous small holes. Slightly bursting sound being heard on holding the drug tightly near the car. Texture light and fragile, easily broken, fracture often showing noodle crystals. Odour, characteristically stinking taste, weak.
本品呈不规则块状。黄色或略呈绿黄色。表面不平坦，呈脂肪光泽，常有多数小孔。用手握紧置于耳旁，可闻轻微的爆裂声。体轻，质松，易碎，断面常呈针状结晶形。有特异的臭气，味淡。

Identification 鉴别

Melts easily on burning, with a blue flame and an irritant odour of sulfur dioxide.
本品燃烧时易熔融，火焰为蓝色，并有二氧化硫的刺激性臭气。

Assay 含量测定

To about 0.2 g of the fine powder, accurately weighed, in a conical flask, add 50 ml of ethanolic potassium hydroxide (0.5 mol/L) VS. accurately measured, and 10 ml of water, heat on a water hath to dissolve and evaporate the ethanol until no bubble and no odour of ethanol are produced in the solution. Add 40 ml of water, place a small funnel on the mouth of the flask, boil gently for 10 minutes, allow to cool, add dropwise carefully 5 ml of hydrogen peroxide TS, mix well, beat on a boiling water bath for 10 minutes, coal to room temperature, wash the funnel and the inner wall of the flask with water, add 2 drops of methyl orange IS, and titrate with hydrochloric acid (0.5 mol/L ) VS. Perform a blank determination and make a necessary correction. Each ml of ethanolic potassium hydroxide (0.5 mol/L) VS is equivalent 8.015 mg of sulfur (S).
取本品细粉约0.2g，精密称定，置锥形瓶中，精密加入乙醇制氢氧化钾滴定液（0.5mol/L）50ml，加水10ml，置水浴中加热使溶解，并挥去乙醇（直至无气泡、无醇臭）。加水40ml，于瓶颈插入一小漏斗，微沸10分钟，冷却，小心滴加过氧化氢试液5ml，摇匀，置沸水浴中加热10分钟，冷却至室温，用水冲洗漏斗及瓶内壁，加入甲基橙指示液2滴，用盐酸滴定液（0.5mol/L）滴定，并将滴定结果用空白试验校正。每1ml乙醇制氢氧化钾滴定液（0.5mol/L）相当于8.015mg的硫（S）。

Prepared slices 饮片

Sulfur 硫黄

Processing 炮制

Eliminate foreign matter, and break to pieces.
除去杂质，敲成碎块。

Sulfur (processed) 制硫黄

Boil the clean sulfur with bean curd until the bean curd shows blackish-green, take out, wash clean, and dry in the shade.
取净硫黄块，与豆腐同煮，至豆腐显黑绿色时，取出，漂净，阴干。

Property 性

Warm.
温。

Flavor 味

Sour.
酸。

Meridian tropism 归经

Kidney and large intestine meridians.
归肾、大肠经。

Actions 功能

Topical application: To remove toxin and kill worms to treat sore. Oral administration: tonify fire, assist yang and open the bowels.
外用解毒杀虫疗疮；内服补火助阳通便。

Indications 主治

Topical application: scabies and tinea, favus, yin flat-abscesses, and malignant sores; oral administration: Impotence, cold feet, dyspnea of deficiency type cold asthma, and deficiency cold constipation.
外治用于疥癣，秃疮，阴疽恶疮；内服用于阳痿足冷，虚喘冷哮，虚寒便秘。

Dosage 用量

Appropriate amount for topical application, ground into powder and mixed with oil for applyment. Oral administration: 1.5-3 g, used in pills or powder after processed.
外用适量，研末油调涂敷患处。内服1.5～3g，炮制后入丸散服。

Precautions and Warnings 注意

Use cautiously in pregnant woman. Incompatible with Natrii Sulfas, Natrii Sulfas Exsiccatus.
孕妇慎用。不宜与芒硝、玄明粉同用。

Storage 贮藏

Preserve in a dry place, and protect from fire.
置干燥处，防火。