This product is the dried whole plant of Lysimachia christinae Hance, a plant from the Primulaceae family. It is harvested in summer and autumn, impurities are removed, and then it is dried in the sun.
根据《中国药典·2020年版·一部》记载：本品为报春花科植物过路黄Lysimachia christinae Hance 的干燥全草。夏、秋二季采收，除去杂质，晒干。
NMM ID | nmm-01aa |
Systematic Name | Lysimachia christinae Herb |
Systematic Chinese Name | 过路黄全草（guò lù huáng quán cǎo） |
Generic Name | Jin-qian-cao |
Generic Chinese Name | 金钱草（jīn qián cǎo） |
NMM Type | plant |
Species Origins | Lysimachia christinae | 过路黄 |
Medicinal Parts | herb | 全草 |
Special Descriptions | |
Processing Methods | |
Systematic Name Explanation | This product is the dried whole plant of Lysimachia christinae Hance, a plant from the Primulaceae family. It is harvested in summer and autumn, impurities are removed, and then it is dried in the sun. |
Generic Name Explanation | NMMGN follows the Chinese name of the relevant Chinese medicinal materials in the Chinese Pharmacopoeia: 2020 edition: Volume I. |
Parent NMM | |
Child NMMs | |
Creators | |
Reviewers |
金钱草
English text reference: *Chinese Pharmacopoeia (2020 Edition) *
中文文本参考：《中国药典（2020年版）》
Overview 概述
Lysimachia Herb is the dried aerial part of Lysimachia christinae Hance (Fam. Primulaceae). The drug is collected in summer and autumn, removed from impurities, and dried.
本品为报春花科植物过路黄Lysimachia christinae Hance的干燥全草。夏、秋二季采收，除去杂质，晒干。
Description 性状
The drug is often tangled into a mass, hairless or sparsely pubescent. Stems twisted, surface brown or dark reddish-brown, with longitudinal ridges, sometimes with adventitious roots at lower nodes, solid in cross-section. Leaves opposite, mostly wrinkled and crumpled, when flattened, broadly ovate or cordate, 1-4 cm long, 1-5 cm wide, slightly concave at base, entire at margin; upper surface grayish-green or brownish-brown, lower surface lighter, main veins distinctly raised, when soaked in water, black or brown stripes visible by transmitted light; petiole 1-4 cm long. Some with flowers, yellow, solitary in leaf axils, with long pedicels. Capsule globose. Odour, faint; taste, insipid.
本品常缠结成团，无毛或被疏柔毛。茎扭曲，表面棕色或暗棕红色，有纵纹，下部茎节上有时具须根，断面实心。叶对生，多皱缩，展平后呈宽卵形或心形，长1～4 cm，宽1～5 cm，基部微凹，全缘；上表面灰绿色或棕褐色，下表面色较浅，主脉明显突起，用水浸后，对光透视可见黑色或褐色条纹；叶柄长1～4 cm。有的带花，花黄色，单生叶腋，具长梗。蒴果球形。气微，味淡。
Identification 鉴别
（1）Transverse section of stem: Epidermal cells covered with a cuticle, sometimes glandular hairs visible, head cells single, stalk cells 1-2. Cork layer wide[1], some cells containing reddish-brown secretions; secretory ducts scattered, surrounded by 5-10 secretory cells, containing reddish-brown block secretions; endodermis distinct. Medullary sheath fibres arranged in interrupted rings, walls slightly lignified. Phloem narrow. Xylem arranged in rings. Pith often hollow. Thin-walled cells containing starch grains.
（1）本品茎横切面：表皮细胞外被角质层，有时可见腺毛，头部单细胞，柄部1～2细胞。栓内层宽广[1]，细胞中有的含红棕色分泌物；分泌道散在，周围分泌细胞5～10个，内含红棕色块状分泌物；内皮层明显。中柱鞘纤维断续排列成环，壁微木化。韧皮部狭窄。木质部连接成环。髓常成空腔。薄壁细胞含淀粉粒。
Leaf surface: Glandular hairs reddish-brown, head cells single, nearly circular, 25 μm in diameter, stalk cells single. Secretory ducts scattered in leaf parenchyma, 45 μm in diameter, containing reddish-brown secretions. Non-glandular hairs visible on stems and leaf surfaces, 1-17 cells, straight or curved, some cells constricted, 59-1070 μm long, 13-53 μm in diameter at base, surface with fine striations, cell cavity containing yellowish-brown substance.
叶表面观：腺毛红棕色，头部单细胞，类圆形，直径25 μm，柄单细胞。分泌道散在于叶肉组织内，直径45 μm，含红棕色分泌物。被疏毛者茎、叶表面可见非腺毛，1-17细胞，平直或弯曲，有的细胞呈缢缩状，长59～1070 μm，基部直径13～53 μm，表面可见细条纹，胞腔内含黄棕色物。
（2）To 1 g of the powder add 50 ml of 80% methanol, heat under reflux for 1 hour, cool, filter, evaporate the filtrate to dryness, dissolve the residue in 10 ml of water, extract with two 10-ml portions of ether, discard the ether layer, add 10 ml of dilute hydrochloric acid to the aqueous layer, heat in a water bath for 1 hour, remove, cool rapidly, extract with two 20-ml portions of ethyl acetate, combine the ethyl acetate layers, wash with 30 ml of water, discard the aqueous layer, evaporate the ethyl acetate layer to dryness, dissolve the residue in 1 ml of methanol as the test solution. Prepare a solution containing 0.5 mg of quercetin CRS and a solution containing 0.5 mg of kaempferol CRS in methanol as the Reference solution. Carry out the method for thin layer chromatography <0502>, using silica gel G as the coating substance and a mixture of toluene-ethyl acetate-formic acid (10: 8: 1) as the mobile phase. Apply separately to the plate 5 μl of the test solution and 2 μl of each of the Reference solutions. After developing and removal of the plate, dry in air. Spray with a 3% solution of aluminium chloride in ethanol, heat at 105 °C for a few minutes, examine under ultraviolet light at 365 nm. The fluorescent spots in the chromatogram obtained with the test solution correspond in position and colour to the spots in the chromatogram obtained with the Reference solutions.
（2）取本品粉末1 g，加80%甲醇50 ml，加热回流1小时，放冷，滤过，滤液蒸干，残渣加水10 ml使溶解，用乙醚振摇提取2次，每次10 ml，弃去乙醚液，水液加稀盐酸10 ml，置水浴中加热1小时，取出，迅速冷却，用乙酸乙酯振摇提取2次，每次20 ml，合并乙酸乙酯液，用水30 ml洗涤，弃去水液，乙酸乙酯液蒸干，残渣加甲醇1 ml使溶解，作为供试品溶液。另取槲皮素对照品、山柰酚对照品，加甲醇制成每1 ml各含0.5 mg的溶液，作为对照品溶液。照薄层色谱法（通则0502）试验，吸取供试品溶液5 μl、对照品溶液各2 μl，分别点于同一硅胶G薄层板上，以甲苯-甲酸乙酯-甲酸（10：8：1）为展开剂，展开，取出，晾干，喷以3%三氯化铝乙醇溶液，在105°C加热数分钟，置紫外光灯（365 nm）下检视。供试品色谱中，在与对照品色谱相应的位置上，显相同颜色的荧光斑点。
Examination 检查
Impurities 杂质
Not more than 8.0 per cent <2301>.
不得过8%（通则2301）。
Water 水分
Not more than 13.0 per cent <0832, method 2>.
不得过13.0%（通则0832第二法）。
Total ash 总灰分
Not more than 13.0 per cent <2302>.
不得过13.0%（通则2302）。
Acid-insoluble ash 酸不溶性灰分
Not more than 5.0 per cent <2302>.
不得过5.0%（通则2302）。
Extractives 浸出物
Carry out the method for determination of ethanol-soluble Extractives <2201, the hot maceration method>, using 75% ethanol as the solvent, not less than 8.0 per cent.
照醇溶性浸出物测定法（通则2201）项下的热浸法测定，用75%乙醇作溶剂，不得少于8.0%。
Assay 含量测定
Carry out the method for high performance liquid chromatography <0512>.
照高效液相色谱法（通则0512）测定。
Chromatographic conditions and system suitability test 色谱条件与系统适用性试验
Use octadecylsilane bonded silica gel as the filler; use methanol-0.4% phosphoric acid solution (50: 50) as the mobile phase; detection wavelength is 360 nm. The theoretical plate number calculated from the quercetin peak should not be less than 2500.
以十八烷基硅烷键合硅胶为填充剂；以甲醇-0.4%磷酸溶液（50：50）为流动相；检测波长为360 nm。理论板数按槲皮素峰计算应不低于2500。
Preparation of reference solution 对照品溶液的制备
Accurately weigh an appropriate amount of quercetin CRS and kaempferol CRS, add 80% methanol to make a solution containing 4 μg of quercetin and 20 μg of kaempferol per ml.
取槲皮素对照品、山柰酚对照品适量，精密称定，加80%甲醇制成每1 ml各含槲皮素4 μg、山柰酚20 μg的溶液，即得。
Preparation of test solution 供试品溶液的制备
Accurately weigh about 1.5 g of the powder (passed through a No. 3 sieve) of the drug, place it in a stoppered conical flask, accurately add 50 ml of 80% methanol, stopper tightly, weigh, heat under reflux for 1 hour, cool, weigh again, make up the loss in weight with 80% methanol, shake well, filter. Accurately measure 25 ml of the filtrate, accurately add 5 ml of hydrochloric acid, heat in a water bath at 90°C for 1 hour, remove, cool rapidly, transfer to a 50 ml volumetric flask, dilute with 80% methanol to the mark, shake well, filter, take the filtrate, and set aside.
取本品粉末（过三号筛）约1.5 g，精密称定，置具塞锥形瓶中，精密加入80%甲醇50 ml，密塞，称定重量，加热回流1小时，放冷，再称定重量，用80%甲醇补足减失的重量，摇匀，滤过。精密量取续滤液25 ml，精密加入盐酸5 ml，置90 ℃水浴中加热水解1小时，取岀，迅速冷却，转移至50 ml量瓶中，用80%甲醇稀释至刻度，摇匀，滤过，取续滤液，即得。
Assay method 测定法
Accurately draw 10 μl of each of the reference solution and the test solution, inject into the liquid chromatograph, and determine.
分别精密吸取对照品溶液与供试品溶液各10 μl，注入液相色谱仪，测定，即得。
Calculated on the dried basis, the total content of quercetin (C15H10O7) and kaempferol (C15H10O6) should not be less than 0.10%.
本品按干燥品计算，含槲皮素（C15H10O7）和山柰酚（C15H10O6）的总量不得少于0.10%。
Prepared slices 饮片
Lysimachia Herb 金钱草
Processing 炮制
Eliminate Foreign matter, rinse with Water, cut into sections, and dry.
除去杂质，抢水洗，切段，干燥。
Description 性状
In irregular sections. Stems brown or dark brown, striated longitudinally, fracture solid. Leaves opposite, when whole, broadly ovate or cordate; the upper surface greyish-green or dark brown, the lower surface pale in colour, midrib distinctly prominent, the black or brown stripes visible against the light after soaking in water. Occasionally flowers, yellow, solitary vein. Odour, slight; taste, weak.
本品为不规则的段。茎棕色或暗棕红色，有纵纹，实心。叶对生，展平后呈宽卵形或心形，上表面灰绿色或棕褐色，下表面色较浅，主脉明显突出，用水浸后，对光透视可见黑色或褐色的条纹。偶见黄色花，单生叶腋。气微，味淡。
Identification 鉴别
As required for the crude drug.
同药材。
Examination 检查
Water 水分
As required for the crude drug.
同药材。
Total ash 总灰分
As required for the crude drug.
同药材。
Acid-insoluble ash 酸不溶性灰分
As required for the crude drug.
同药材。
Extractives 浸出物
As required for the crude drug.
同药材。
Assay 含量测定
As required for the crude drug.
同药材。
Property 性
Slightly cold.
微寒。
Flavor 味
Sweet and salty.
甘、咸。
Meridian tropism 归经
Liver, gallbladder, kidney, and bladder meridians.
归肝、胆、肾、膀胱经。
Actions 功能
To eliminate dampness and relieve jaundice, promote diuresis and relieve stranguria, detoxify and reduce swelling.
利湿退黄，利尿通淋，解毒消肿。
Indications 主治
Used for damp-heat jaundice, distension and pain in the hypochondrium, urinary calculi, hot stranguria, painful urination, carbuncles and furuncles, snake and insect bites.
用于湿热黄疸，胆胀胁痛，石淋，热淋，小便涩痛，痈肿疔疮，蛇虫咬伤。
Dosage 用量
15-60 g.
15～60 g。
Administration 用法
None.
无。
Storage 贮藏
Preserve in a dry place.
置干燥处。
金钱草
Text reference: Chinese Pharmacopoeia (2015 Edition)
文本参考：《中国药典（2015年版）》
Overview 概述
Christina Loosestrife is the dried herb of Lysimachia christinae Hance (Fam. Primulaceae). The drug is collected in summer and autumn, removed from foreign matter, and dried in the sun.
本品为报春花科植物过路黄Lysimachia christinae Hance的干燥全草。夏、秋二季采收，除去杂质，晒干。
Description 性状
Frequently twisted into masses, glabrous or sparsely pubescent. Stems twisted, externally brown or dark brownish-red, striated longitudinally, stem nodes of the lower part sometimes with rootlets, fracture solid. Leaves opposite, mostly crumpled, when whole, broadly ovate or cordate, 1-4 cm long, 1-5 cm wide, base slightly concave, margin entire; the upper surface greyish-green or dark brown, the lower surface pale in colour, midrib distinctly prominent, after soaking in water, the black or brown stripes visible under the light; petioles 1-4 cm long. Some with flowers, yellow, solitary and axillary, long-petioled. Capsules globose. Odour, slight; taste, weak.
本品常缠结成团，无毛或被疏柔毛。茎扭曲，表面棕色或暗棕红色，有纵纹，下部茎节上有时具须根，断面实心。叶对生，多皱缩，展平后呈宽卵形或心形，长1～4cm，宽 1～5cm，基部微凹，全缘；上表面灰绿色或棕褐色，下表面色较浅，主脉明显突起，用水浸后，对光透视可见黑色或褐色条纹；叶柄长1～4cm。有的带花，花黄色，单生叶腋，具长梗。蒴果球形。气微，味淡。
Identification 鉴别
叶表面观：腺毛红棕色，头部单细胞，类圆形，直径25µm，柄单细胞。分泌道散在于叶肉组织内，直径45µm，含红棕色分泌物。被疏毛者茎、叶表面可见非腺毛，1～17细胞，平直或弯曲，有的细胞呈缢缩状，长59～1070µm，基部直径13～53µm，表面可见细条纹，胞腔内含黄棕色物。
（1）本品茎横切面：表皮细胞外被角质层，有时可见腺毛，头部单细胞，柄部1～2细胞。栓内层宽广，细胞中有的含红棕色分泌物；分泌道散在，周围分泌细胞5～10个，内含红棕色块状分泌物；内皮层明显。中柱鞘纤维断续排列成环，壁微木化。韧皮部狭窄。木质部连接成环。髓常成空腔。薄壁细胞含淀粉粒。
Examination 检查
Foreign matter 杂质
Not more than 8 per cent <2301>.
不得过8%（通则2301）。
Water 水分
Not more than 13.0 per cent <0832, method 2>.
不得过13.0%（通则0832第二法）。
Total ash 总灰分
Not more than 13.0 per cent <2302>.
不得过13.0%（通则2302）。
Acid-insoluble ash 酸不溶性灰分
Not more than 5.0 per cent <2302>.
不得过5.0%（通则2302）。
Extractives 浸出物
Carry out the method for determination of ethanol-soluble extractives <2201, the hot extraction method>, using 75% ethanol as the solvent, not less than 8.0 per cent.
照醇溶性浸出物测定法（通则2201）项下的热浸法测定，用75%乙醇作溶剂，不得少于8.0%。
Assay 含量测定
Carry out the method for high performance liquid chromatography <0512>.
照高效液相色谱法（通则0512）测定。
以十八烷基硅烷键合硅胶为填充剂；以甲醇-0.4%磷酸溶液（50：50）为流动相；检测波长为360nm。理论板数按槲皮素峰计算应不低于2500。
色谱条件与系统适用性试验
Property 性
Mild cold; sweet and salty.
甘、咸，微寒。
Flavor 味
Weak cold.
微寒。
Meridian tropism 归经
Liver, gallbladder, kidney, and bladder meridians.
归肝、胆、肾、膀胱经。
Actions 功能
To drain dampness, abate jaundice, disinhibit urine, relieve stranguria, remove toxin, and relieve swelling.
利湿退黄，利尿通淋，解毒消肿。
Indications 主治
Dampness-heat jaundice, gallbladder distention, hypochondriac pain, stone strangury, heat strangury, difficult and painful urination, swelling abscess, deep-rooted boil, sore, and bites of insect, worm, or snake.
用于湿热黄疸，胆胀胁痛，石淋，热淋，小便涩痛，痈肿疔疮，蛇虫咬伤。
Dosage 用量
15-60 g.
15～60g。
Administration 用法
No special requirements.
无特殊要求。
Storage 贮藏
Preserve in a dry place.
置干燥处。
This product is the dried whole plant of Lysimachia christinae Hance, a plant from the Primulaceae family. It is harvested in summer and autumn, impurities are removed, and then it is dried in the sun.
本天然药材为报春花科植物过路黄Lysimachia christinae Hance 的干燥全草。夏、秋二季采收，除去杂质，晒干。