紫石英

English text reference: Chinese Pharmacopoeia (2020 Edition)

Overview

Fluorite is the mineral fluorite of the family Fluoritum. It mainly contains calcium fluoride (CaF2). After mining, remove impurities.

Description

It is irregularly shaped and angular, with a blocky or granular aggregate. It is purple or green, uneven in depth, and has white streaks. It is translucent to transparent and has a glassy luster. The surface often has cracks. The texture is hard and brittle, and it is easily broken. It has a slight odor and a mild taste.

Identification

（1）To 0.1g of the powder add 2ml of hydrochloric acid and 5ml of 4% boric acid solution in a beaker, heat to dissolve at a gentle boil. Take 1 drop of the solution and place it on a microscope slide, add 1 drop of sulfuric acid (1→4) to the slide, let it stand for a while, and observe under a microscope. Needle-shaped crystals can be seen.

（2）Observe the sample under ultraviolet light (365nm), showing bright purple or purple to bluish-purple fluorescence.

（3）Take 20mg of the powder and 15mg of silica powder, mix well, place it in a dry test tube with a rubber stopper wrapped in tin foil, add 10 drops of sulfuric acid. Take another fine glass tube through the rubber stopper, wet the lower end of the glass tube with a drop of water, insert the stopper about 3.5cm from the bottom of the test tube, carefully heat the bottom of the test tube (on an asbestos board), when the water droplet moves up and down, stop heating for about 1 minute, then continue heating until a thick white smoke is emitted. After standing for 2-3 minutes, remove the stopper and glass tube, rinse the lower end of the glass tube with 2-3 drops of water to flow into the crucible, add 1 drop of ammonium molybdate solution [take 3g of ammonium molybdate, dissolve in 60ml of water, then add 20ml of nitric acid solution (1→2), shake well], slightly heat, the solution appears pale yellow, after standing for 1-2 minutes, add 1 drop of aniline solution (take 1g of aniline, dissolve in 10% acetic acid to make 100ml) and 1-2 drops of saturated sodium acetate solution, it will turn blue or form a blue precipitate.

Content determination

Take about 0.1g of the powder, accurately weigh it, place it in a conical flask, add 2ml of hydrochloric acid and 5ml of 4% boric acid solution, heat to dissolve, add 300ml of water, 10% triethanolamine solution 10ml, and 1 drop of methyl red indicator, drop 10% potassium hydroxide solution until the solution turns yellow, then continue to add 15ml, and add about 30mg of calcium yellow-green indicator, titrate with ethylenediaminetetraacetic acid disodium titration solution (0.05mol/L) until the yellow-green fluorescence of the solution disappears and turns orange. Each 1ml of ethylenediaminetetraacetic acid disodium titration solution (0.05mol/L) is equivalent to 3.904mg of calcium fluoride (CaF2).

The content of calcium fluoride (CaF2) in the sample should not be less than 85.0%.

Prepared slices

Fluorite

Processing

Remove impurities and crush into pieces.

Description

It is irregularly shaped and fragmented. It is purple or green, translucent to transparent, and has a glassy luster. It has a slight odor and a mild taste.

Identification

Same as the crude drug.

Content determination

Same as the crude drug.

Calcined Fluorite

Processing

Take clean fluorite blocks, calcine them according to the calcination and quenching method <0213>, and quench with vinegar.

For every 100kg of purple quartz, 30kg of vinegar is used.

Description

It is irregularly shaped and fragmented or in powder form. The surface is yellowish-white, brown, or purple, without luster. The texture is crisp. It has a vinegar aroma and a mild taste.

Content determination

Same as the crude drug, the content of calcium fluoride (CaF2) should not be less than 80.0%.

Identification

Same as the crude drug（1）and（3）.

Property

Warm.

Flavor

Sweet.

Meridian tropism

Kidney, heart, and lung meridians.

Actions

Warm the kidney and warm the uterus, calm the mind and soothe the nerves, warm the lungs and relieve asthma.

Indications

Used for deficiency of kidney yang, cold uterus and infertility, palpitations and restlessness, insomnia and excessive dreaming, and cold cough and asthma.

Dosage

9-15g.

Administration

Decoct first.

Storage

Store in a dry place.

紫石英

Text reference: Chinese Pharmacopoeia (2015 Edition)

Overview

Fluorite is a mineral of fluorides of fluorite group, containing mainly calcium fluoride (CaF2). The drug is collected and removed from foreign matter.

Description

Aggregates of granules or masses. In irregular pieces with angularities, purple or green, uneven in color, streak white. Translucent to transparent, with a glassy luster. Externally often with crevices. Texture hard and fragile, easily broken. Odor, slight; taste, weak.

Identification

（2）取本品，置紫外光灯（365nm）下观察，显亮紫色、紫色至青紫色荧光。

Examination

Water

Not more than 14.0 per cent <0832, method 2>.

Total ash

Not more than 8.0 per cent <2302>.

Extractives

Carry out the method for determination of ethanol-soluble Extractives <2201, the cold maceration method>, using anhydrous ethanol as the solvent, not less than 1.9 per cent.

Prepared slices

Fluorite

Processing

Eliminate foreign matter, break into pieces.

In irregular masses, purple or green, transparent or semi-transparent, with a glassy luster. Odor, slightly; taste, weak.

Identification

【鉴别】同药材。

Fluorite(calcined with vinegar)

每100kg紫石英，用醋30kg。

In irregular masses or powder, externally yellowish-white, brown or purple, lackluster. Texture crisp. Has a vinegar aroma, taste weak.

【鉴别】（1）、（3）同药材。

Property and Flavor

Warm; sweet. Meridian tropism Kidney, heart, and lung meridians.

Actions and Indications

To warm the kidney and uterus, calm the heart, tranquilize the mind, warm the lung, and relieve wheezing. Used for deficiency of kidney yang, infertility caused by uterine coldness, fright palpitations and unrest, insomnia, dream-disturbed sleep, deficiency cold wheezing, and cough.

Administration and Dosage

9-15 g. It should be decocted first.

Storage

Preserve in a dry place.