自然铜

English text reference: Chinese Pharmacopoeia (2020 Edition)

Overview

Pyrite is the mineral of the sulfide class, belonging to the pyrite group of the pyrite family, mainly containing iron disulfide (FeS2). After mining, remove impurities.

Description

Pyrite crystals are mostly cubic, and aggregates are dense blocks. The surface is bright yellow with a metallic luster; some are yellow-brown or brownish-brown without a metallic luster. It has stripes, and the streaks are green-black or brown-red. The body is heavy, hard or slightly brittle, easy to crush, the fracture surface is yellow-white with a metallic luster; or the fracture surface is brownish-brown, and silver-white bright stars can be seen.

Identification

Take 1g of the powder, add 4ml of dilute hydrochloric acid, shake, filter, and the filtrate shows the identification reaction of ferric salt (General Rule 0301).

Content Determination

Take about 0.25g of the fine powder, accurately weigh it, place it in a porcelain crucible, ignite it at about 650°C for about 30 minutes, take it out, let it cool, transfer the calcined substance to a conical flask, add 15ml of hydrochloric acid and 3ml of 25% potassium fluoride solution, cover the surface dish, heat to a slight boil, dropwise add 6% stannous chloride solution, shake continuously, wait for complete decomposition, leaving only white residue at the bottom of the bottle, wash the surface dish and the inner wall of the bottle with a small amount of water, dropwise add 6% stannous chloride solution to a light yellow color (if there is an excess of stannous chloride, dropwise add potassium permanganate solution to a light yellow color), add 100ml of water and 15 drops of 25% sodium tungstate solution, and dropwise add 1% titanium trichloride solution to a blue color, then carefully add potassium dichromate titration solution (0.01667mol/L) until the blue color just fades, immediately add 10ml of sulfuric acid-phosphoric acid-water (2:3:5) and 10 drops of 0.5% sodium diphenylamine sulfonate solution, titrate with potassium dichromate titration solution (0.01667mol/L) until the solution shows a stable blue-purple color. Each 1ml of potassium dichromate titration solution (0.01667mol/L) is equivalent to 5.585mg of iron (Fe).

The iron (Fe) content of this product should be 40.0% to 55.0%.

Prepared Slices

Pyrite

Processing

Pyrite is purified by removing impurities, washing, and drying. Crush before use.

Description

Same as the crude drug.

Calcined Pyrite

Processing

Take purified pyrite, calcine it according to the calcination and quenching method <0213> until it is dark red, quench it with vinegar until the surface turns blackish-brown, the luster disappears, and it becomes crispy.

For every 100kg of pyrite, use 30kg of vinegar.

Description

This product is small cubic or irregular granules or powder, brownish-brown to blackish-brown or gray-black, without metallic luster. The texture is crispy. Slightly acidic odor.

Content Determination

Same as the crude drug. The iron (Fe) content of this product should not be less than 40.0%.

Identification

Same as the crude drug.

Property

Neutral.

Flavor

Pungent.

Meridian tropism

Liver meridian.

Actions

Dispels blood stasis and relieves pain, promotes the healing of tendons and bones.

Indications

Used for contusions, fractures of tendons and bones, and pain and swelling caused by blood stasis.

Dosage

3-9g. External use appropriate amount.

Administration

Mostly made into pills or powder for oral administration. If used in decoction, it is advisable to decoct it first.

Storage

Place in a dry place.

自然铜

Text reference: Chinese Pharmacopoeia (2015 Edition)

Overview

Pyrite is a mineral of sulfides of pyrite group, containing mainly iron sulfide(FeS).The drug is collected, and removed from foreign matter.

Description

Cube-like crystals, aggregated in dense masses, externally bright pale yellow, with lustre of metal, some yellowish-brown or dark brown, without lustre of metal.Streaks greenish-black or brownish-red.Texture heavy and hard or slightly fragile, easily broken.Fracture yellowish-white, with lustre of metal, or brown, with silvery sparkle.

Identification

To 1 g of the powder add 4 ml of dilute hydrochloric acid TS, shake and filter. The filtrate yields the reactions characteristic of ferric salts 〈0301〉.

Prepared slices

Pyrite

Processing

Eliminate foreign matter, wash clean, dry. Break to pieces before use.

Pyrite (calcined)

Calcine the clean Pyrite as described under the method for calcining openly 〈0213〉 to dark red, quench with vinegar until the colour of the surface turns to blackish-brown, lustre disappears and the texture becomes loose.

Using 30 kg of vinegar per 100 kg of Pyrite.

Property

Pungent.

Flavor

Neutral.

Meridian tropism

Liver meridian.

Actions

To dissipate stasis, relieve pain, reconnect sinews and bones.

Indications

Traumatic injuries, sinew injury and fracture, stasis, swelling and pain.

Dosage

3-9 g.

Administration

Usually used in pills or powder, and should be decocted first for decoction. Appropriate amount for topical application.

Storage

Preserve in a dry place.