紫石英

English text reference: Chinese Pharmacopoeia (2020 Edition)
中文文本参考：《中国药典（2020年版）》

Overview 概述

Fluorite is the mineral fluorite of the family Fluoritum. It mainly contains calcium fluoride (CaF2). After mining, remove impurities.
本品为氟化物类矿物萤石族萤石，主含氟化钙（CaF2）。采挖后，除去杂石。

Description 性状

It is irregularly shaped and angular, with a blocky or granular aggregate. It is purple or green, uneven in depth, and has white streaks. It is translucent to transparent and has a glassy luster. The surface often has cracks. The texture is hard and brittle, and it is easily broken. It has a slight odor and a mild taste.
本品为块状或粒状集合体。呈不规则块状，具棱角。紫色或绿色，深浅不匀，条痕白色。半透明至透明，有玻璃样光泽。表面常有裂纹。质坚脆，易击碎。气微，味淡。

Identification 鉴别

（1）To 0.1g of the powder add 2ml of hydrochloric acid and 5ml of 4% boric acid solution in a beaker, heat to dissolve at a gentle boil. Take 1 drop of the solution and place it on a microscope slide, add 1 drop of sulfuric acid (1→4) to the slide, let it stand for a while, and observe under a microscope. Needle-shaped crystals can be seen.
（1）取本品细粉0.1g，置烧杯中，加盐酸2ml与4%硼酸溶液5ml，加热微沸使溶解。取溶液1滴，置载玻片上，加硫酸溶液（1→4）1滴，静置片刻，置显微镜下观察，可见针状结晶。

（2）Observe the sample under ultraviolet light (365nm), showing bright purple or purple to bluish-purple fluorescence.
（2）取本品，置紫外光灯（365nm）下观察，显亮紫色、紫色至青紫色荧光。

（3）Take 20mg of the powder and 15mg of silica powder, mix well, place it in a dry test tube with a rubber stopper wrapped in tin foil, add 10 drops of sulfuric acid. Take another fine glass tube through the rubber stopper, wet the lower end of the glass tube with a drop of water, insert the stopper about 3.5cm from the bottom of the test tube, carefully heat the bottom of the test tube (on an asbestos board), when the water droplet moves up and down, stop heating for about 1 minute, then continue heating until a thick white smoke is emitted. After standing for 2-3 minutes, remove the stopper and glass tube, rinse the lower end of the glass tube with 2-3 drops of water to flow into the crucible, add 1 drop of ammonium molybdate solution [take 3g of ammonium molybdate, dissolve in 60ml of water, then add 20ml of nitric acid solution (1→2), shake well], slightly heat, the solution appears pale yellow, after standing for 1-2 minutes, add 1 drop of aniline solution (take 1g of aniline, dissolve in 10% acetic acid to make 100ml) and 1-2 drops of saturated sodium acetate solution, it will turn blue or form a blue precipitate.
（3）取本品细粉20mg与二氧化硅粉15mg，混匀，置具外包锡纸的橡皮塞的干燥试管中，加硫酸10滴。另取细玻璃管穿过橡皮塞，玻璃管下端沾水一滴，塞置距试管底部约3.5cm处，小心加热（在石棉板上）试管底部，见水滴上下移动时，停止加热约1分钟，再继续加热，至有浓厚的白烟放出为止。放置2～3分钟，取下塞与玻璃管，用2～3滴水冲洗玻璃管下端使流入坩埚内，加钼酸铵溶液［取钼酸铵3g，加水60ml溶解后，再加入硝酸溶液（1→2）20ml，摇匀］1滴，稍加热，溶液显淡黄色，放置1～2分钟后，加联苯胺溶液（取联苯胺1g，加入10%醋酸使溶解成100ml）1滴和饱和醋酸钠溶液1～2滴，即显蓝色或生成蓝色沉淀。

Content determination 含量测定

Take about 0.1g of the powder, accurately weigh it, place it in a conical flask, add 2ml of hydrochloric acid and 5ml of 4% boric acid solution, heat to dissolve, add 300ml of water, 10% triethanolamine solution 10ml, and 1 drop of methyl red indicator, drop 10% potassium hydroxide solution until the solution turns yellow, then continue to add 15ml, and add about 30mg of calcium yellow-green indicator, titrate with ethylenediaminetetraacetic acid disodium titration solution (0.05mol/L) until the yellow-green fluorescence of the solution disappears and turns orange. Each 1ml of ethylenediaminetetraacetic acid disodium titration solution (0.05mol/L) is equivalent to 3.904mg of calcium fluoride (CaF2).
取本品细粉约0.1g，精密称定，置锥形瓶中，加盐酸2ml与4%硼酸溶液5ml，加热溶解后，加水300ml、10%三乙醇胺溶液10ml与甲基红指示剂1滴，滴加10%氢氧化钾溶液至溶液显黄色，再继续多加15ml，并加钙黄绿素指示剂约30mg，用乙二胺四醋酸二钠滴定液（0.05mol/L）滴定至溶液黄绿色荧光消失而显橙色。每1ml乙二胺四醋酸二钠滴定液（0.05mol/L）相当于3.904mg的氟化钙（CaF2）。

The content of calcium fluoride (CaF2) in the sample should not be less than 85.0%.
本品含氟化钙（CaF2）不得少于85.0%。

Prepared slices 饮片

Fluorite 紫石英

Processing 炮制

Remove impurities and crush into pieces.
除去杂石，砸成碎块。

Description 性状

It is irregularly shaped and fragmented. It is purple or green, translucent to transparent, and has a glassy luster. It has a slight odor and a mild taste.
本品为不规则碎块。紫色或绿色，半透明至透明，有玻璃样光泽。气微，味淡。

Identification 鉴别

Same as the crude drug.
同药材。

Content determination 含量测定

Same as the crude drug.
同药材。

Calcined Fluorite 煅紫石英

Processing 炮制

Take clean fluorite blocks, calcine them according to the calcination and quenching method <0213>, and quench with vinegar.
取净紫石英块，照煅淬法（通则0213）煅透，醋淬。

For every 100kg of purple quartz, 30kg of vinegar is used.
每100kg紫石英，用醋30kg。

Description 性状

It is irregularly shaped and fragmented or in powder form. The surface is yellowish-white, brown, or purple, without luster. The texture is crisp. It has a vinegar aroma and a mild taste.
本品为不规则碎块或粉末。表面黄白色、棕色或紫色，无光泽。质酥脆。有醋香气，味淡。

Content determination 含量测定

Same as the crude drug, the content of calcium fluoride (CaF2) should not be less than 80.0%.
同药材，含氟化钙（CaF2）不得少于80.0%。

Identification 鉴别

Same as the crude drug（1）and（3）.
（1）、（3）同药材。

Property 性

Warm.
温。

Flavor 味

Sweet.
甘。

Meridian tropism 归经

Kidney, heart, and lung meridians.
归肾、心、肺经。

Actions 功能

Warm the kidney and warm the uterus, calm the mind and soothe the nerves, warm the lungs and relieve asthma.
温肾暖宫，镇心安神，温肺平喘。

Indications 主治

Used for deficiency of kidney yang, cold uterus and infertility, palpitations and restlessness, insomnia and excessive dreaming, and cold cough and asthma.
用于肾阳亏虚，宫冷不孕，惊悸不安，失眠多梦，虚寒咳喘。

Dosage 用量

9-15g.
9～15g。

Administration 用法

Decoct first.
先煎。

Storage 贮藏

Store in a dry place.
置干燥处。

紫石英

Text reference: Chinese Pharmacopoeia (2015 Edition)
文本参考：《中国药典（2015年版）》

Overview 概述

Fluorite is a mineral of fluorides of fluorite group, containing mainly calcium fluoride (CaF2). The drug is collected and removed from foreign matter.
本品为氟化物类矿物萤石族萤石，主含氟化钙（CaF2）。采挖后，除去杂石。

Description 性状

Aggregates of granules or masses. In irregular pieces with angularities, purple or green, uneven in color, streak white. Translucent to transparent, with a glassy luster. Externally often with crevices. Texture hard and fragile, easily broken. Odor, slight; taste, weak.
本品为块状或粒状集合体。呈不规则块状，具棱角。紫色或绿色，深浅不匀，条痕白色。半透明至透明，有玻璃样光泽。表面常有裂纹。质坚脆，易击碎。气微，味淡。

Identification 鉴别

（2）取本品，置紫外光灯（365nm）下观察，显亮紫色、紫色至青紫色荧光。
（1）取本品细粉0.1g，置烧杯中，加盐酸2ml与4%硼酸溶液5ml，加热微沸使溶解。取溶液1滴，置载玻片上，加硫酸溶液（1→4）1滴，静置片刻，置显微镜下观察，可见针状结晶。

Examination 检查

Water 水分

Not more than 14.0 per cent <0832, method 2>.
不得过14.0%（通则0832第二法）。

Total ash 总灰分

Not more than 8.0 per cent <2302>.
不得过8.0%（通则2302）。

Extractives 浸出物

Carry out the method for determination of ethanol-soluble Extractives <2201, the cold maceration method>, using anhydrous ethanol as the solvent, not less than 1.9 per cent.
照醇溶性浸出物测定法（通则2201）项下的冷浸法测定，用无水乙醇作溶剂，不得少于1.9%。

Prepared slices 饮片

Fluorite 紫石英

Processing 炮制

Eliminate foreign matter, break into pieces.
除去杂石，砸成碎块。

In irregular masses, purple or green, transparent or semi-transparent, with a glassy luster. Odor, slightly; taste, weak.
本品为不规则碎块。紫色或绿色，半透明至透明，有玻璃样光泽。气微，味淡。

Identification 鉴别

【鉴别】同药材。
【含量测定】同药材。

Fluorite(calcined with vinegar) 煅紫石英

每100kg紫石英，用醋30kg。
取净紫石英块，照煅淬法（通则0213）煅透，醋淬。

In irregular masses or powder, externally yellowish-white, brown or purple, lackluster. Texture crisp. Has a vinegar aroma, taste weak.
本品为不规则碎块或粉末。表面黄白色、棕色或紫色，无光泽。质酥脆。有醋香气，味淡。

【鉴别】（1）、（3）同药材。
【含量测定】同药材，含氟化钙（CaF2）不得少于80.0%。

Property and Flavor 性味与归经

Warm; sweet. Meridian tropism Kidney, heart, and lung meridians.
甘，温。归肾、心、肺经。

Actions and Indications 功能与主治

To warm the kidney and uterus, calm the heart, tranquilize the mind, warm the lung, and relieve wheezing. Used for deficiency of kidney yang, infertility caused by uterine coldness, fright palpitations and unrest, insomnia, dream-disturbed sleep, deficiency cold wheezing, and cough.
温肾暖宫，镇心安神，温肺平喘。用于肾阳亏虚，宫冷不孕，惊悸不安，失眠多梦，虚寒咳喘。

Administration and Dosage 用法与用量

9-15 g. It should be decocted first.
9～15g，先煎。

Storage 贮藏

Preserve in a dry place.
置干燥处。