九香虫

English text reference: Chinese Pharmacopoeia (2020 Edition)
中文文本参考：《中国药典（2020年版）》

Overview 概述

Aspongopus is the dried body of Aspongopus chinensis Dallas (Fam. Pentatomidae). It is collected from November to March of the following year, placed in a suitable container, suffocated with a small amount of alcohol, taken out and dried; or killed by scalding in boiling water, taken out and dried.
本品为蝽科昆虫九香虫Aspongopus chinensis Dallas的干燥体。11月至次年3月前捕捉，置适宜容器内，用酒少许将其闷死，取出阴干；或置沸水中烫死，取出，干燥。

Description 性状

The drug is slightly hexagonal and flat-elliptical, measuring 1.6-2 cm long and about 1 cm wide. The surface is brownish-brown or brownish-black with a slight luster. The head is small and slightly triangular with the thorax. The compound eyes are prominent and oval, with a single pair of ocelli and a pair of antennae, each with 5 segments, most of which have fallen off. There are 2 pairs of wings on the back, the outer pair of which is hard at the base and the inner pair is membranous and transparent. There are 3 pairs of legs on the thorax, most of which have fallen off. The abdomen is reddish-brown to brownish-black, with small protrusions near the edges of each segment. The texture is brittle, and there is a light brown internal substance when broken. It has a peculiar odor and a slightly salty taste.
本品略呈六角状扁椭圆形，长1.6～2cm，宽约1cm。表面棕褐色或棕黑色，略有光泽。头部小，与胸部略呈三角形，复眼突出，卵圆状，单眼1对，触角1对各5节，多已脱落。背部有翅2对，外面的1对基部较硬，内部1对为膜质，透明。胸部有足3对，多已脱落。腹部棕红色至棕黑色，每节近边缘处有突起的小点。质脆，折断后腹内有浅棕色的内含物。气特异，味微咸。

Identification 鉴别

To 0.2g of the powder add 20 ml of petroleum ether (60-90°C) and treat with ultrasound for 20 minutes. Filter, wash the residue with petroleum ether 3 times, each time with 5 ml, combine the washings and the filtrate, and concentrate to 10 ml as the test solution. Take 0.2g of the reference drug of Aspongopus, and prepare the reference drug solution in the same way. Take the reference substance of oleic acid, add petroleum ether (60-90°C) to make a solution containing 5 mg per ml as the reference solution. Carry out the method for thin layer chromatography<0502>, using silica gel G as the coating substance and a mixture of petroleum ether (60-90°C), ether, and glacial acetic acid (36:9:0.9) as the mobile phase. Place the plate in a developing tank pre-saturated with the mobile phase for 20 minutes, develop, remove, dry, and expose to iodine vapor until the spots are clearly visible. The chromatogram obtained with the test solution shows spots of the same color at the corresponding positions as the chromatogram of the reference drug and the chromatogram of the reference solution.
取本品粉末0.2g，加石油醚（60～90°C）20ml超声处理20分钟，滤过，药渣用石油醚洗涤3次，每次5ml，合并洗液及滤液，浓缩至10ml，作为供试品溶液。另取九香虫对照药材0.2g，同法制成对照药材溶液。再取油酸对照品，加石油醚（60～90°C）制成每1ml含5mg的溶液，作为对照品溶液。照薄层色谱法（通则0502）试验，吸取上述三种溶液各2μl，分别点于同一硅胶G薄层板上，以石油醚（60～90°C）-乙醚-冰醋酸（36:9:0.9）为展开剂，置用展开剂预饱和20分钟的展开缸内，展开，取出，晾干，置碘蒸气中熏至斑点显色清晰。供试品色谱中，在与对照药材色谱和对照品色谱相应的位置上，显相同颜色的斑点。

Examination 检查

Water 水分

Not more than 9.0 per cent <0832,method 2>.
不得过9.0%（通则0832第二法）。

Total ash 总灰分

Not more than 6.0 per cent <2302>.
不得过6.0%（通则2302）。

Aflatoxin 黄曲霉毒素

Determine according to the method for determination of mycotoxins <2351>.
照真菌毒素测定法（通则2351）测定。

Take about 5g of the powder of this product (passed through a No.2 sieve), accurately weigh, add 3g of sodium chloride, prepare the test solution according to the method for preparation of test solution of aflatoxins, and then accurately take 10ml of the supernatant for determination and calculation.
取本品粉末（过二号筛）约5g，精密称定，加入氯化钠3g， 照黄曲霉毒素测定法项下供试品溶液的制备方法，其中，精密量取上清液10ml，测定，计算，即得。

The content of aflatoxin B1 in this product shall not exceed 5μg per 1000g, and the total content of aflatoxin G2, aflatoxin G1, aflatoxin B2, and aflatoxin B1 shall not exceed 10μg.
本品每1000g含黄曲霉毒素B1不得过5μg，含黄曲霉毒素G2、黄曲霉毒素G1、黄曲霉毒素B2和黄曲霉毒素B1的总量不得过10μg。

Extractives 浸出物

Carry out the method for determination of ethanol-soluble Extractives <2201>, using diluted ethanol as the solvent, not less than 10.0 per cent.
照醇溶性浸出物测定法（通则2201）项下的热浸法测定，用稀乙醇作溶剂，不得少于10.0%。

Prepared slices 饮片

Fructus Evodiae 九香虫

Processing 炮制

Remove impurities.
除去杂质。

Description 性状

Same as the crude drug.
同药材。

Identification 鉴别

Same as the crude drug.
同药材。

Examination 检查

Same as the crude drug.
同药材。

Extractives 浸出物

Same as the crude drug.
同药材。

Stir-fried Fructus Evodiae 炒九香虫

Processing 炮制

Take clean Fructus Evodiae, stir-fry according to the method of stir-frying <0213> until fragrant.
取净九香虫，照清炒法（通则0213）炒至有香气。

Description 性状

This product is shaped like Fructus Evodiae. The surface is dark brown to black with a shiny oily luster. It has a slight fishy odor and a slightly burnt aroma, with a slightly salty taste.
本品形如九香虫。表面棕黑色至黑色，显油润光泽。气微腥，略带焦香气，味微咸。

Examination 检查

Water 水分

Water content, same as the crude drug, not more than 7.0 per cent.
同药材，不得过7.0%。

Property 性

warm in nature.
温。

Flavor 味

Salty.
咸。

Meridian tropism 归经

It enters the liver, spleen, and kidney meridians.
归肝、脾、肾经。

Actions 功能

Regulate qi and relieve pain, warm the middle and assist yang.
理气止痛，温中助阳。

Indications 主治

Used for stomach cold and distension pain, liver and stomach qi pain, kidney deficiency and impotence, and lumbago and knee pain.
用于胃寒胀痛，肝胃气痛，肾虚阳痿，腰膝酸痛。

Dosage 用量

3-9g.
3～9g。

Administration 用法

None.
无。

Storage 贮藏

Store in a wooden box lined with oil paper to prevent moisture and moth.
置木箱内衬以油纸，防潮、防蛀。

九香虫

Text reference: Chinese Pharmacopoeia (2015 Edition)
文本参考：《中国药典（2015年版）》

Overview 概述

Stink-bug is the dried body of Aspongopus chinensis Dallas (Fam. Pentatomidae). The drug is collected from November to the next March, placed in an appropriate container, suffocated with wine, then taken out and dried； or scalded to death by boiling water, taken out, and dried.
本品为蝽科昆虫九香虫Aspongopus chinensis Dallas的干燥体。11月至次年3月前捕捉，置适宜容器内，用酒少许将其闷死，取出阴干；或置沸水中烫死，取出，干燥。

Description 性状

Somewhat hexagonal and flattened ellipsoidal, 1.6-2 cm long, about 1 cm wide. Externally brown or brownish-black, slightly lustrous. Small head and thorax slightly triangular； compound eyes protruded, ovoid, ocellus one pair； a pair of antennae each with 5 segments, usually fallen off. Dorsum bearing 2 pairs of wings, the outer pair relatively hard at the basal, the inner pair membranous and transparent. Thorax bearing 3 pairs of legs, usually fallen off. Abdomen brownish-red to brownish-black, each segment with projected small points near the margin. Texture fragile, pale brown contents in abdomen visible when broken. Odour, characteristic ； taste, slightly salty.
本品略呈六角状扁椭圆形，长1.6～2cm，宽约lcm。表面棕褐色或棕黑色，略有光泽。头部小，与胸部略呈三角形，复眼突出，卵圆状，单眼1对，触角1对各5节，多已脱落。背部有翅2对，外面的1对基部较硬，内部1对为膜质，透明。胸部有足3对，多已脱落。腹部棕红色至棕黑色，每节近边缘处有突起的小点。质脆，折断后腹内有浅棕色的内含物。气特异，味微咸。

Identification 鉴别

To 0.2 g of the powder add 20 ml of petroleum ether (60-90℃) , ultrasonicate for 20 minutes and filter, wash the residue with three 5-ml quantities of petroleum ether, combine the filtrate and the washings, and concentrate to 10 ml as the test solution. Prepare a solution of 0.2 g of Aspongopus reference drug in the same manner as the reference drug solution. Dissolve oleic acid CRS in petroleum ether (60-90℃)to produce a solution containing 5 mg per ml as the reference solution. Carry out the method for thin layer chromatography<0502>, using silica gel G as the coating substance and a mixture of petroleum ether (60-90℃),ethyl acetate and glacial acetic acid (36 : 9 : 0.9) as the mobile phase. Apply separately to the plate 2 μl of each of the above three solutions. After developing in a chamber pre-saturated with the mobile phase for 20 minutes and removal of the plate, dry in air, expose to iodine vapour to the spots clear. The spots in the chromatogram obtained with the test solution correspond in position and colour to the spots obtained with the reference drug solution and the reference solution.
取本品粉末0.2g，加石油醚（60～90℃）20ml超声处理20分钟，滤过，药渣用石油醚洗涤3次，每次5ml，合并洗液及滤液，浓缩至10ml，作为供试品溶液。另取九香虫对照药材0.2g，同法制成对照药材溶液。再取油酸对照品，加石油醚（60～90℃）制成每1ml含5mg的溶液，作为对照品溶液。照薄层色谱法（通则0502）试验，吸取上述三种溶液各2μl，分别点于同一硅胶G薄层板上，以石油醚（60～90℃）-乙醚-冰醋酸（36：9：0.9）为展开剂，置用展开剂预饱和20分钟的展开缸内，展开，取出，晾干，置碘蒸气中熏至斑点显色清晰。供试品色谱中，在与对照药材色谱和对照品色谱相应的位置上，显相同颜色的斑点。

Examination 检查

Total ash 总灰分

Not more than 6.0 per cent<2302>.
不得过6.0%（通则2302）。

Extractives 浸出物

Carry out the method for determination of ethanol-soluble Extractives <2201 , the hot extraction method>, using dilute ethanol as the solvent, not less than 10.0 per cent.
照醇溶性浸出物测定法（通则2201）项下的热浸法测定，用稀乙醇作溶剂，不得少于10.0%。

Prepared slices 饮片

Stink-bug 九香虫

Processing 炮制

Eliminate Foreign matter,spray with Water , soften briefly, cut into sections, and dry in the sun.
除去杂质，喷淋清水，稍润，切段，干燥。

Property 性

Warm.
温。

Flavor 味

Salty.
咸。

Meridian tropism 归经

Liver, spleen and kidney meridians.
归肝、脾、肾经。

Actions 功能

To regulate qi, relieve pain, warm the middle energizer and assist yang.
理气止痛，温中助阳。

Indications 主治

Stomach cold and distending pain, qi pain in liver and stomach, impotence caused by kidney deficiency, sore pain in the lower back and knees.
用于胃寒胀痛，肝胃气痛，肾虚阳痿，腰膝酸痛。

Dosage 用量

3-9 g.
3～9g。

Administration 用法

No special requirements.
无特殊要求。

Storage 贮藏

Preserve in wood boxes lined with wax paper, and protect from moisture and moth.
置木箱内衬以油纸，防潮、防蛀。